Literature DB >> 17563805

Subfemtomole level protein sequencing by Edman degradation carried out in a microfluidic chip.

Wenzhang Chen1, Xuefeng Yin, Jinxia Mu, Yan Yin.   

Abstract

A novel microfluidic chip based Edman degradation system is developed, in which Edman degradation can be carried out with peptide at a subfemtomole level; combined with MALDI-TOF-MS detection, the identification specificity of gel-separated protein in low abundance has been drastically improved.

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Year:  2007        PMID: 17563805     DOI: 10.1039/b700200a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Multi-channel microfluidic chip coupling with mass spectrometry for simultaneous electro-sprays and extraction.

Authors:  Cilong Yu; Fei Tang; Xiang Qian; Yan Chen; Quan Yu; Kai Ni; Xiaohao Wang
Journal:  Sci Rep       Date:  2017-12-12       Impact factor: 4.379

  1 in total

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