Literature DB >> 175631

Chemotherapeutic effects of some alkylating derivatives of nitrosourea on the development of tumors transplacentally induced in rats by ENU.

D Schiffer, M T Giordana, S Pezzotta, P Paoletti.   

Abstract

The application of BCNU, CCNU and MeCCNU has been shown to greatly reduce the number of tumors induced in rats by transplacentally administered ENU and to inhibit the full development of tumor proliferation. Moreover, no neurinomas appeared after treatment with CCNU. The application of GCNU proved to be much less effective. Our statistics in the form of tables showing these findings are included and discussed.

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Year:  1976        PMID： 175631     DOI： 10.1007/bf00684940

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  14 in total

1.  [Early stages of tumors in the central nervous system. Experimental morphological studies].

Authors:  W Jänisch; D Schreiber; R Warzok; G Osske
Journal:  Exp Pathol (Jena)       Date:  1970

2.  Effect of chemotherapy and-or head irradiation on survival of mice with intracranial glioma.

Authors:  J M Thomson; Y Maruyama; S Schwartz; E Hahn
Journal:  Radiology       Date:  1971-10       Impact factor: 11.105

3.  Experimental brain tumours induced in rats by nitrosourea derivatives. II. Morphological aspects of nitrosoethylurea tumours obtained by transplacental induction.

Authors:  E Grossi-Paoletti; P Paoletti; D Schiffer; A Fabiani
Journal:  J Neurol Sci       Date:  1970-12       Impact factor: 3.181

4.  Differential staining of acid glycosaminoglycans (mucopolysaccharides) by alcian blue in salt solutions.

Authors:  J E Scott; J Dorling
Journal:  Histochemie       Date:  1965-10-01

5.  An experimental model for selective production of neoplasms of the peripheral nervous system.

Authors:  R H Denlinger; A Koestner; J A Swenberg
Journal:  Acta Neuropathol       Date:  1973-02-19       Impact factor: 17.088

6.  Development of an animal brain tumor model and its response to therapy with 1,3-bis(2-chloroethyl)-1-nitrosourea.

Authors:  M Barker; T Hoshino; O Gurcay; C B Wilson; S L Nielsen; R Downie; J Eliason
Journal:  Cancer Res       Date:  1973-05       Impact factor: 12.701

7.  Tumors of the nervous system induced by ethylnitrosourea administered either intracerebrally of subcutaneously to newborn rats. Morphological and biochemical characteristics.

Authors:  E Grossi-Paoletti; P Paoletti; S Pezzotta; D Schiffer; A Fabiani
Journal:  J Neurosurg       Date:  1972-11       Impact factor: 5.115

8.  Studies on the chemotherapy of experimental brain tumors: evaluation of 1,3-bis(2-chloroethyl)-l-nitrosourea, cyclophosphamide, mithramycin, and methotrexate.

Authors:  W R Shapiro; J I Ausman; D P Rall
Journal:  Cancer Res       Date:  1970-09       Impact factor: 12.701

9.  The effects of 1,3-bis(2-chloroethyl)-1-nitrosurea on survival and cell progression in Chinese hamster cells.

Authors:  S C Barranco; R M Humphrey
Journal:  Cancer Res       Date:  1971-02       Impact factor: 12.701

10.  Some effects of 1, 3-bis(2-chloroethyl)-1-nitrosourea upon the synthesis of protein and nucleic acids in vivo and in vitro.

Authors:  G P Wheeler; B J Bowdon
Journal:  Cancer Res       Date:  1965-11       Impact factor: 12.701
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  7 in total

Review 1.  Glioblastoma multiforme: morphology and biology.

Authors:  K Jellinger
Journal:  Acta Neurochir (Wien)       Date:  1978       Impact factor: 2.216

2.  Pathology of human malignant gliomas after radiation and chemotherapy.

Authors:  D Schiffer; M T Giordana; P Paoletti; R Soffietti; L Tarenzi
Journal:  Acta Neurochir (Wien)       Date:  1980       Impact factor: 2.216

3.  Combination chemotherapy (COMP protocol) and radiotherapy of anaplastic supratentorial gliomas.

Authors:  K Jellinger; P Kothbauer; D Volc; R Vollmer; R Weiss
Journal:  Acta Neurochir (Wien)       Date:  1979       Impact factor: 2.216

4.  Morphological changes in anaplastic gliomas treated with radiation and chemotherapy.

Authors:  L Gerstner; K Jellinger; W D Heiss; G Wöber
Journal:  Acta Neurochir (Wien)       Date:  1977       Impact factor: 2.216

5.  Detection of acid mucopolysaccharides in human brain tumors by histochemical methods.

Authors:  A Engelhardt
Journal:  Acta Neuropathol       Date:  1980       Impact factor: 17.088

6.  Cerebral tumors induced by transplacental ENU: study of the different tumoral stages, particularly of early proliferations.

Authors:  D Schiffer; M T Giordana; S Pezzotta; C Lechner; P Paoletti
Journal:  Acta Neuropathol       Date:  1978-01-19       Impact factor: 17.088

7.  Cerebral tumours induced by ENU; changes of adenylate cyclase activity in the tumour latency time.

Authors:  G Racagni; M T Giordana; S Pezzotta; F Bruno; P Paoletti; D Schiffer
Journal:  Acta Neurochir (Wien)       Date:  1979       Impact factor: 2.216
  7 in total

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