Literature DB >> 17562800

Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital.

Azita Leavitt1, Shiri Navon-Venezia, Inna Chmelnitsky, Mitchell J Schwaber, Yehuda Carmeli.   

Abstract

Carbapenem resistance due to KPC has rarely been observed outside the United States. We noticed a sharp increase in carbapenem-resistant Klebsiella pneumoniae strains possessing KPC in Tel Aviv Medical Center from 2004 to 2006. Sixty percent of the isolates belonged to a single clone susceptible only to gentamicin and colistin and carried the bla(KPC-3) gene, while almost all other clones carried the bla(KPC-2) gene. This rapid dissemination of KPC outside the United States is worrisome.

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Year:  2007        PMID: 17562800      PMCID: PMC1932543          DOI: 10.1128/AAC.00299-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  23 in total

Review 1.  Emerging carbapenemases in Gram-negative aerobes.

Authors:  P Nordmann; L Poirel
Journal:  Clin Microbiol Infect       Date:  2002-06       Impact factor: 8.067

2.  Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center.

Authors:  Neil Woodford; Philip M Tierno; Katherine Young; Luke Tysall; Marie-France I Palepou; Elaina Ward; Ronald E Painter; Deborah F Suber; Daniel Shungu; Lynn L Silver; Kenneth Inglima; John Kornblum; David M Livermore
Journal:  Antimicrob Agents Chemother       Date:  2004-12       Impact factor: 5.191

3.  Molecular characterization of a beta-lactamase gene, blaGIM-1, encoding a new subclass of metallo-beta-lactamase.

Authors:  Mariana Castanheira; Mark A Toleman; Ronald N Jones; Franz J Schmidt; Timothy R Walsh
Journal:  Antimicrob Agents Chemother       Date:  2004-12       Impact factor: 5.191

4.  Plasmid-mediated carbapenem-hydrolysing beta-lactamase KPC-2 in carbapenem-resistant Serratia marcescens isolates from Hangzhou, China.

Authors:  Rong Zhang; Hong Wei Zhou; Jia Chang Cai; Gong-Xiang Chen
Journal:  J Antimicrob Chemother       Date:  2007-01-24       Impact factor: 5.790

5.  Characterization of OXA-25, OXA-26, and OXA-27, molecular class D beta-lactamases associated with carbapenem resistance in clinical isolates of Acinetobacter baumannii.

Authors:  M Afzal-Shah; N Woodford; D M Livermore
Journal:  Antimicrob Agents Chemother       Date:  2001-02       Impact factor: 5.191

6.  Metallo-beta-lactamases in clinical Pseudomonas isolates in Taiwan and identification of VIM-3, a novel variant of the VIM-2 enzyme.

Authors:  J J Yan; P R Hsueh; W C Ko; K T Luh; S H Tsai; H M Wu; J J Wu
Journal:  Antimicrob Agents Chemother       Date:  2001-08       Impact factor: 5.191

7.  Plasmid-mediated, carbapenem-hydrolysing beta-lactamase, KPC-2, in Klebsiella pneumoniae isolates.

Authors:  Ellen Smith Moland; Nancy D Hanson; Vicki L Herrera; Jennifer A Black; Thomas J Lockhart; Ashfaque Hossain; Judith A Johnson; Richard V Goering; Kenneth S Thomson
Journal:  J Antimicrob Chemother       Date:  2003-03       Impact factor: 5.790

8.  Isolation of an integron-borne blaVIM-4 type metallo-beta-lactamase gene from a carbapenem-resistant Pseudomonas aeruginosa clinical isolate in Hungary.

Authors:  Balázs Libisch; Mária Gacs; Károly Csiszár; Mónika Muzslay; László Rókusz; Miklós Füzi
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

9.  Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 beta-lactamases in New York City.

Authors:  Patricia A Bradford; Simona Bratu; Carl Urban; Melissa Visalli; Noriel Mariano; David Landman; James J Rahal; Steven Brooks; Sanda Cebular; John Quale
Journal:  Clin Infect Dis       Date:  2004-06-14       Impact factor: 9.079

10.  Genetic and functional analysis of the chromosome-encoded carbapenem-hydrolyzing oxacillinase OXA-40 of Acinetobacter baumannii.

Authors:  Claire Héritier; Laurent Poirel; Daniel Aubert; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2003-01       Impact factor: 5.191

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  82 in total

1.  Comparative evaluation of combined-disk tests using different boronic acid compounds for detection of klebsiella pneumoniae carbapenemase-producing enterobacteriaceae clinical isolates.

Authors:  Athanassios Tsakris; Katerina Themeli-Digalaki; Aggeliki Poulou; Georgia Vrioni; Evangelia Voulgari; Vasiliki Koumaki; Antonella Agodi; Spyros Pournaras; Danai Sofianou
Journal:  J Clin Microbiol       Date:  2011-06-01       Impact factor: 5.948

2.  A pilot survey of carbapenem-resistant Escherichia coli and Klebsiella pneumoniae mediated by K pneumoniae serine carbapenemases in a regional referral hospital in British Columbia.

Authors:  Aubrey Shannon; Ken Wagner; Naowarat Cheeptham; Gwen Stephens
Journal:  Can J Infect Dis Med Microbiol       Date:  2011       Impact factor: 2.471

3.  Complete nucleotide sequence of KPC-3-encoding plasmid pKpQIL in the epidemic Klebsiella pneumoniae sequence type 258.

Authors:  Azita Leavitt; Inna Chmelnitsky; Yehuda Carmeli; Shiri Navon-Venezia
Journal:  Antimicrob Agents Chemother       Date:  2010-08-09       Impact factor: 5.191

4.  Comparison of BD Phoenix, Vitek 2, and MicroScan automated systems for detection and inference of mechanisms responsible for carbapenem resistance in Enterobacteriaceae.

Authors:  Neil Woodford; Anne T Eastaway; Michael Ford; Alistair Leanord; Chloe Keane; Reinhard M Quayle; Jane A Steer; Jiancheng Zhang; David M Livermore
Journal:  J Clin Microbiol       Date:  2010-06-09       Impact factor: 5.948

5.  Imipenem disc for detection of KPC carbapenemase-producing Enterobacteriaceae in clinical practice.

Authors:  Shmuel Benenson; Violeta Temper; Matan J Cohen; Carmela Schwartz; Carlos Hidalgo-Grass; Colin Block
Journal:  J Clin Microbiol       Date:  2011-02-02       Impact factor: 5.948

6.  Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in Klebsiella pneumoniae isolate from Greece.

Authors:  Gaelle Cuzon; Thierry Naas; Marie Claude Demachy; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2007-12-03       Impact factor: 5.191

7.  Rapid Identification of Five Classes of Carbapenem Resistance Genes Directly from Rectal Swabs by Use of the Xpert Carba-R Assay.

Authors:  Nicholas M Moore; Rafael Cantón; Edoardo Carretto; Lance R Peterson; Robert L Sautter; Maria M Traczewski
Journal:  J Clin Microbiol       Date:  2017-05-17       Impact factor: 5.948

Review 8.  Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions.

Authors:  L S Tzouvelekis; A Markogiannakis; M Psichogiou; P T Tassios; G L Daikos
Journal:  Clin Microbiol Rev       Date:  2012-10       Impact factor: 26.132

9.  Evaluation of boronic acid disk tests for differentiating KPC-possessing Klebsiella pneumoniae isolates in the clinical laboratory.

Authors:  Athanassios Tsakris; Ioulia Kristo; Aggeliki Poulou; Katerina Themeli-Digalaki; Alexandros Ikonomidis; Dimitra Petropoulou; Spyros Pournaras; Danai Sofianou
Journal:  J Clin Microbiol       Date:  2008-12-10       Impact factor: 5.948

10.  Clinical and Demographic Characteristics of Patients With a New Diagnosis of Carriage or Clinical Infection With Carbapenemase-Producing Enterobacterales: A Retrospective Study.

Authors:  Assaf Adar; Hiba Zayyad; Maya Azrad; Kozita Libai; Ilana Aharon; Orna Nitzan; Avi Peretz
Journal:  Front Public Health       Date:  2021-02-05
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