Literature DB >> 17561383

Enforcing Ostwald's rule of stages: isolation of paracetamol forms III and II.

Jonathan C Burley1, Melinda J Duer, Robin S Stein, Ranko M Vrcelj.   

Abstract

We have been able to isolate and study the polymorphic form III of paracetamol using a specially designed methodology. Our work represents the first report of a reproducible, reliable route to form III. This has been an outstanding problem for over quarter of a century. Our method may be applicable to the isolation of metastable polymorphs of other compounds.

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Year:  2007        PMID: 17561383     DOI: 10.1016/j.ejps.2007.04.002

Source DB:  PubMed          Journal:  Eur J Pharm Sci        ISSN: 0928-0987            Impact factor:   4.384


  8 in total

1.  Τhe role of surface energy in the apparent solubility of two different calcite crystal habits.

Authors:  Eftychios Hadjittofis; Silvia M Vargas; James D Litster; Kyra L Sedransk Campbell
Journal:  Proc Math Phys Eng Sci       Date:  2021-08-25       Impact factor: 2.704

2.  Monitoring model drug microencapsulation in PLGA scaffolds using X-ray powder diffraction.

Authors:  Adeyinka Aina; Manish Gupta; Yamina Boukari; Andrew Morris; Nashiru Billa; Stephen Doughty
Journal:  Saudi Pharm J       Date:  2015-03-21       Impact factor: 4.330

3.  Drug-Polymer Interactions in Acetaminophen/Hydroxypropylmethylcellulose Acetyl Succinate Amorphous Solid Dispersions Revealed by Multidimensional Multinuclear Solid-State NMR Spectroscopy.

Authors:  Andrea Pugliese; Michael Toresco; Daniel McNamara; Dinu Iuga; Anuji Abraham; Michael Tobyn; Lucy E Hawarden; Frédéric Blanc
Journal:  Mol Pharm       Date:  2021-08-10       Impact factor: 4.939

4.  Exploring the role of crystal habit in the Ostwald rule of stages.

Authors:  Eftychios Hadjittofis; Silvia M Vargas; James D Litster; Kyra L Sedransk Campbell
Journal:  Proc Math Phys Eng Sci       Date:  2022-02-09       Impact factor: 2.704

5.  Challenging the Ostwald rule of stages in mechanochemical cocrystallisation.

Authors:  Luzia S Germann; Mihails Arhangelskis; Martin Etter; Robert E Dinnebier; Tomislav Friščić
Journal:  Chem Sci       Date:  2020-08-12       Impact factor: 9.825

Review 6.  Mechanochemistry: A Green Approach in the Preparation of Pharmaceutical Cocrystals.

Authors:  Mizraín Solares-Briones; Guadalupe Coyote-Dotor; José C Páez-Franco; Miriam R Zermeño-Ortega; Carmen Myriam de la O Contreras; Daniel Canseco-González; Alcives Avila-Sorrosa; David Morales-Morales; Juan M Germán-Acacio
Journal:  Pharmaceutics       Date:  2021-05-25       Impact factor: 6.321

7.  Surface Mediated Structures: Stabilization of Metastable Polymorphs on the Example of Paracetamol.

Authors:  Heike M A Ehmann; Oliver Werzer
Journal:  Cryst Growth Des       Date:  2014-07-07       Impact factor: 4.076

8.  Enhanced NMR Discrimination of Pharmaceutically Relevant Molecular Crystal Forms through Fragment-Based Ab Initio Chemical Shift Predictions.

Authors:  Joshua D Hartman; Graeme M Day; Gregory J O Beran
Journal:  Cryst Growth Des       Date:  2016-10-04       Impact factor: 4.076

  8 in total

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