Literature DB >> 17560367

The coming of age for Piwi proteins.

Anita G Seto1, Robert E Kingston, Nelson C Lau.   

Abstract

Piwi proteins, a subfamily of Argonaute (Ago) proteins, have recently been shown to bind endogenous small RNAs. However, differences between Ago proteins (which bind microRNAs and small interfering RNAs) and Piwi proteins and Piwi-interacting RNAs (piRNAs) suggest novel functions for Piwi proteins. Here, we highlight the recent progress in understanding Piwi function and the implications for germline and stem cell development.

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Year:  2007        PMID: 17560367     DOI: 10.1016/j.molcel.2007.05.021

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  119 in total

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