Literature DB >> 175599

In vitro transformation of chicken bone marrow cells with avian erythroblastosis virus.

T Graf.   

Abstract

An in vitro transformation of bone marrow cells has been demonstrated for two strains of avian erythroblastosis virus (AEV-R and AEV-ES4). The transformed cells were indistinguishable from in vivo transformed erythroblasts in morphology and staining characteristics and could be propagated to large numbers. The transformation efficiency could be greatly increased by the addition of dimethylsulfoxide (DMSO). The number of foci appearing in the presence of DMSO was proportional to the virus concentration.

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Year:  1975        PMID： 175599     DOI： 10.1515/znc-1975-11-1232

Source DB:  PubMed          Journal:  Z Naturforsch C Biosci        ISSN： 0341-0382


  9 in total

1.  Tumor specificity of acute avian leukemia viruses reflected by their transformation target cell specificity in vitro.

Authors:  T Graf; B Royer-Pokora; W Meyer-Glauner; H Beug
Journal:  Med Microbiol Immunol       Date:  1977       Impact factor: 3.402

2.  Creation of a chimeric oncogene: analysis of the biochemical and biological properties of v-erbB/src fusion polypeptide.

Authors:  M L Privalsky
Journal:  J Virol       Date:  1987-06       Impact factor: 5.103

3.  Mutagenesis of the avian erythroblastosis virus erbB coding region: an intact extracellular domain is not required for oncogenic transformation.

Authors:  M Bassiri; M L Privalsky
Journal:  J Virol       Date:  1986-08       Impact factor: 5.103

4.  Mutant of avian erythroblastosis virus defective for erythroblast transformation: deletion in the erb portion of p75 suggests function of the protein in leukemogenesis.

Authors:  H Beug; G Kitchener; G Doederlein; T Graf; M J Hayman
Journal:  Proc Natl Acad Sci U S A       Date:  1980-11       Impact factor: 11.205

5.  Avian erythroblastosis virus produces two mRNA's.

Authors:  S M Anderson; W S Hayward; B G Neel; H Hanafusa
Journal:  J Virol       Date:  1980-12       Impact factor: 5.103

6.  src- and fps-containing avian sarcoma viruses transform chicken erythroid cells.

Authors:  P Kahn; B Adkins; H Beug; T Graf
Journal:  Proc Natl Acad Sci U S A       Date:  1984-11       Impact factor: 11.205

7.  Comparative tryptic peptide mapping studies suggest a role in cell transformation for the gag-related protein of avian erythroblastosis virus and avian myelocytomatosis virus strains CMII and MC29.

Authors:  G Kitchener; M J Hayman
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

8.  In vitro translation of avian myeloblastosis virus RNA.

Authors:  S M Anderson; J H Chen
Journal:  J Virol       Date:  1981-10       Impact factor: 5.103

9.  Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways.

Authors:  Suraiya Rasheed; Jasper S Yan; Adil Hussain; Bruce Lai
Journal:  J Transl Med       Date:  2009-08-27       Impact factor: 5.531
  9 in total

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