Literature DB >> 17558623

Obesity and metabolic syndrome in a psychiatric rehabilitation service.

Srinivasan Tirupati1, Ling-Ern Chua.   

Abstract

OBJECTIVE: People with schizophrenia and bipolar disorders suffer from increased rates of obesity and metabolic syndrome. Metabolic disorders add to the burden of disease and affect treatment and rehabilitation outcomes. This study aimed to study the prevalence of obesity and metabolic syndrome in people with chronic psychotic disorders in a psychiatric rehabilitation setting.
METHOD: All patients in the psychiatry rehabilitation program were assessed for obesity and metabolic syndrome using the definition of International Diabetes Federation (2005) was conducted as part of clinical protocol recently introduced into practice.
RESULTS: A total of 221 patients were assessed. The prevalence of obesity was 59% and metabolic syndrome 68%. Metabolic syndrome was more frequent in patients receiving polypharmacy with multiple antipsychotics and mood stabilisers. Rates of nontreatment for metabolic disorders ranged from 30% to 88%.
CONCLUSIONS: The rates of obesity and metabolic syndrome in patients with chronic severe mental disorders on antipsychotic drug treatment were 2 to 3 times that in the general population. A majority of them were untreated. Detection, monitoring and appropriate treatment of obesity and metabolic disorders should be a component of an assertive care management program to reduce morbidity and mortality and improve rehabilitation outcomes.

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Year:  2007        PMID: 17558623     DOI: 10.1080/00048670701392841

Source DB:  PubMed          Journal:  Aust N Z J Psychiatry        ISSN: 0004-8674            Impact factor:   5.744


  23 in total

Review 1.  Prevalence and correlates of antipsychotic polypharmacy: a systematic review and meta-regression of global and regional trends from the 1970s to 2009.

Authors:  Juan A Gallego; John Bonetti; Jianping Zhang; John M Kane; Christoph U Correll
Journal:  Schizophr Res       Date:  2012-04-24       Impact factor: 4.939

2.  Safety and tolerability of antipsychotic polypharmacy.

Authors:  Juan A Gallego; Jimmi Nielsen; Marc De Hert; John M Kane; Christoph U Correll
Journal:  Expert Opin Drug Saf       Date:  2012-05-08       Impact factor: 4.250

3.  Cardiovascular risk assessment and management in mental health clients: whose role is it anyway?

Authors:  Amanda J Wheeler; Jeff Harrison; Priya Mohini; Jeshika Nardan; Amy Tsai; Eve Tsai
Journal:  Community Ment Health J       Date:  2009-08-18

4.  Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care.

Authors:  Marc DE Hert; Christoph U Correll; Julio Bobes; Marcelo Cetkovich-Bakmas; Dan Cohen; Itsuo Asai; Johan Detraux; Shiv Gautam; Hans-Jurgen Möller; David M Ndetei; John W Newcomer; Richard Uwakwe; Stefan Leucht
Journal:  World Psychiatry       Date:  2011-02       Impact factor: 49.548

Review 5.  Mania and mortality: why the excess cardiovascular risk in bipolar disorder?

Authors:  Dylan P Murray; Miriam Weiner; Maithri Prabhakar; Jess G Fiedorowicz
Journal:  Curr Psychiatry Rep       Date:  2009-12       Impact factor: 5.285

6.  The prevalence and mechanisms of metabolic syndrome in schizophrenia: a review.

Authors:  Evangelos Papanastasiou
Journal:  Ther Adv Psychopharmacol       Date:  2013-02

7.  Physical and mental factors associated with obesity in individuals with mental disorders attending psychiatric day-care facilities.

Authors:  Michiko Saiga; Takashi Watanabe; Shin-Ichi Yoshioka
Journal:  Yonago Acta Med       Date:  2013-03-01       Impact factor: 1.641

8.  A prospective observational study of obesity, body composition, and insulin resistance in 18 women with bipolar disorder and 17 matched control subjects.

Authors:  Sara B Fleet-Michaliszyn; Isabella Soreca; Amy D Otto; John M Jakicic; Andrea Fagiolini; David J Kupfer; Bret H Goodpaster
Journal:  J Clin Psychiatry       Date:  2008-10-21       Impact factor: 4.384

9.  Characteristics of Medicaid Recipients Receiving Persistent Antipsychotic Polypharmacy.

Authors:  Robert O Cotes; David R Goldsmith; Sarah L Kopelovich; Cathy A Lally; Benjamin G Druss
Journal:  Community Ment Health J       Date:  2017-11-10

10.  Role of Omega-3 fatty acids in preventing metabolic disturbances in patients on olanzapine plus either sodium valproate or lithium: a randomized double-blind placebo-controlled trial.

Authors:  Toktam Faghihi; Adel Jahed; Javad Mahmoudi-Gharaei; Vandad Sharifi; Shahin Akhondzadeh; Padideh Ghaeli
Journal:  Daru       Date:  2012-10-04       Impact factor: 3.117

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