| Literature DB >> 17557852 |
Clemente I Montero1, Matthew R Johnson, Chung-Jung Chou, Shannon B Conners, Sarah G Geouge, Sabrina Tachdjian, Jason D Nichols, Robert M Kelly.
Abstract
Transcriptomes and growth physiologies of the hyperthermophile Thermotoga maritima and an antibiotic-resistant spontaneous mutant were compared prior to and following exposure to chloramphenicol. While the wild-type response was similar to that of mesophilic bacteria, reduced susceptibility of the mutant was attributed to five mutations in 23S rRNA and phenotypic preconditioning to chloramphenicol.Entities:
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Year: 2007 PMID: 17557852 PMCID: PMC1951032 DOI: 10.1128/AEM.00453-07
Source DB: PubMed Journal: Appl Environ Microbiol ISSN: 0099-2240 Impact factor: 4.792