Literature DB >> 17556345

Skeletal absorbed fractions for electrons in the adult male: considerations of a revised 50-microm definition of the bone endosteum.

W E Bolch1, A P Shah, C J Watchman, D W Jokisch, P W Patton, D A Rajon, M Zankl, N Petoussi-Henss, K F Eckerman.   

Abstract

In 1995, the International Commission on Radiological Protection (ICRP) issued ICRP Publication 70 which provided an extensive update to the physiological and anatomical reference data for the skeleton of adults and children originally issued in ICRP Publication 23. Although ICRP Publication 70 has been a valuable document in the development of reference voxel computational phantoms, additional guidance is needed for dose assessment in the skeletal tissues beyond that given in ICRP Publication 30. In this study, a computed tomography (CT) and micro-CT-based model of the skeletal tissues is presented, which considers (1) a 50-microm depth in marrow for the osteoprogenitor cells, (2) electron escape from trabecular spongiosa to the surrounding cortical bone, (3) cortical bone to trabecular spongiosa cross-fire for electrons and (4) variations in specific absorbed fraction with changes in bone marrow cellularity for electrons. A representative data set is given for electron dosimetry in the craniofacial bones of the adult male.

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Year:  2007        PMID: 17556345     DOI: 10.1093/rpd/ncm268

Source DB:  PubMed          Journal:  Radiat Prot Dosimetry        ISSN: 0144-8420            Impact factor:   0.972


  3 in total

1.  An image-based skeletal dosimetry model for the ICRP reference adult male--internal electron sources.

Authors:  Matthew Hough; Perry Johnson; Didier Rajon; Derek Jokisch; Choonsik Lee; Wesley Bolch
Journal:  Phys Med Biol       Date:  2011-03-22       Impact factor: 3.609

2.  A bone marrow toxicity model for ²²³Ra alpha-emitter radiopharmaceutical therapy.

Authors:  Robert F Hobbs; Hong Song; Christopher J Watchman; Wesley E Bolch; Anne-Kirsti Aksnes; Thomas Ramdahl; Glenn D Flux; George Sgouros
Journal:  Phys Med Biol       Date:  2012-05-01       Impact factor: 3.609

Review 3.  Stem cell niches and other factors that influence the sensitivity of bone marrow to radiation-induced bone cancer and leukaemia in children and adults.

Authors:  Richard B Richardson
Journal:  Int J Radiat Biol       Date:  2011-01-04       Impact factor: 2.694

  3 in total

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