| Literature DB >> 17555960 |
Fiona Ronketti1, A Venkata Ramana, Xia Chao-Ming, Livia Pica-Mattoccia, Donato Cioli, Matthew H Todd.
Abstract
Several analogues of the potent anthelmintic praziquantel were prepared with variation in the aromatic ring. The biological activity of these analogues was evaluated and compared against known analogues. Amination of the ring was tolerated while other variations were not. These results have important implications for drug development for schistosomiasis.Entities:
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Year: 2007 PMID： 17555960 DOI： 10.1016/j.bmcl.2007.05.063
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823