| Literature DB >> 17555768 |
C F Lo1.
Abstract
In this communication, based upon the deterministic Gompertz law of cell growth, a stochastic model in tumour growth is proposed. This model takes account of both cell fission and mortality too. The corresponding density function of the size of the tumour cells obeys a functional Fokker--Planck equation which can be solved analytically. It is found that the density function exhibits an interesting "multi-peak" structure generated by cell fission as time evolves. Within this framework the action of therapy is also examined by simply incorporating a therapy term into the deterministic cell growth term.Entities:
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Year: 2007 PMID: 17555768 DOI: 10.1016/j.jtbi.2007.04.024
Source DB: PubMed Journal: J Theor Biol ISSN: 0022-5193 Impact factor: 2.691