OBJECTIVES: To assess contributions of individual lifestyle changes on systolic blood pressure (SBP) changes. METHODS: We examined associations between lifestyle behavior changes and SBP after 6 and 18 months in 782 PREMIER trial participants. RESULTS: In multivariate models omitting weight, predicted SBP reductions ranged from (1)/2 to 1(1)/2 mm Hg for reduced urinary sodium, improved fitness, and adherence to the DASH diet (except sodium at 18 months). With weight included, only fitness change additionally predicted SBP at 18 months. CONCLUSIONS: Several lifestyle behavior changes are important for BP lowering, but are difficult to detect when weight is included in multivariate models.
RCT Entities:
OBJECTIVES: To assess contributions of individual lifestyle changes on systolic blood pressure (SBP) changes. METHODS: We examined associations between lifestyle behavior changes and SBP after 6 and 18 months in 782 PREMIER trial participants. RESULTS: In multivariate models omitting weight, predicted SBP reductions ranged from (1)/2 to 1(1)/2 mm Hg for reduced urinary sodium, improved fitness, and adherence to the DASH diet (except sodium at 18 months). With weight included, only fitness change additionally predicted SBP at 18 months. CONCLUSIONS: Several lifestyle behavior changes are important for BP lowering, but are difficult to detect when weight is included in multivariate models.
Authors: Lee Hooper; Carolyn D Summerbell; Rachel Thompson; Deirdre Sills; Felicia G Roberts; Helen J Moore; George Davey Smith Journal: Cochrane Database Syst Rev Date: 2012-05-16
Authors: Kimberly K Vesco; Njeri Karanja; Janet C King; Matthew W Gillman; Nancy Perrin; Cindy McEvoy; Cara Eckhardt; K Sabina Smith; Victor J Stevens Journal: Contemp Clin Trials Date: 2012-03-20 Impact factor: 2.226