Literature DB >> 17555349

Indole alkaloids produced by a marine fungus isolate of Penicillium janthinellum Biourge.

Olga F Smetanina1, Anatoly I Kalinovsky, Yuliya V Khudyakova, Mikhail V Pivkin, Pavel S Dmitrenok, Sergey N Fedorov, Hong Ji, Jong-Young Kwak, Tatyana A Kuznetsova.   

Abstract

Three new indole alkaloids, shearinines D, E, and F (1-3), together with the known shearinine A (4) were isolated from the marine-derived strain of the fungus Penicillium janthinellum Biourge. The chemical structures of 1-4 were established by 2D NMR and HREIMS data. Shearinines A, D, and E induce apoptosis in human leukemia HL-60 cells, and shearinine E also inhibits EGF-induced malignant transformation of JB6 P+ Cl 41 cells in a soft agar.

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Year:  2007        PMID： 17555349     DOI： 10.1021/np060396d

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  14 in total

1.  Bioguided discovery and pharmacophore modeling of the mycotoxic indole diterpene alkaloids penitrems as breast cancer proliferation, migration, and invasion inhibitors.

Authors:  Asmaa A Sallam; Wael E Houssen; Chris R Gissendanner; Khaled Y Orabi; Ahmed I Foudah; Khalid A El Sayed
Journal:  Medchemcomm       Date:  2013-10       Impact factor: 3.597

Review 2.  Comprehensive Overview on the Chemistry and Biological Activities of Selected Alkaloid Producing Marine-Derived Fungi as a Valuable Reservoir of Drug Entities.

Authors:  Fadia S Youssef; Jesus Simal-Gandara
Journal:  Biomedicines       Date:  2021-04-28

Review 3.  Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents?

Authors:  Nelson G M Gomes; Florence Lefranc; Anake Kijjoa; Robert Kiss
Journal:  Mar Drugs       Date:  2015-06-19       Impact factor: 5.118

Review 4.  Bioactive Compounds Produced by Strains of Penicillium and Talaromyces of Marine Origin.

Authors:  Rosario Nicoletti; Antonio Trincone
Journal:  Mar Drugs       Date:  2016-02-18       Impact factor: 5.118

5.  Imaging mass spectrometry and MS/MS molecular networking reveals chemical interactions among cuticular bacteria and pathogenic fungi associated with fungus-growing ants.

Authors:  Cristopher A Boya P; Hermógenes Fernández-Marín; Luis C Mejía; Carmenza Spadafora; Pieter C Dorrestein; Marcelino Gutiérrez
Journal:  Sci Rep       Date:  2017-07-17       Impact factor: 4.379

Review 6.  A journey under the sea: the quest for marine anti-cancer alkaloids.

Authors:  Rita Tohme; Nadine Darwiche; Hala Gali-Muhtasib
Journal:  Molecules       Date:  2011-11-23       Impact factor: 4.411

7.  Synthesis of (-)-Dihydroraputindole D by Enantioselective Benzoylation of a 1,3-Diol Intermediate.

Authors:  Marvin Fresia; Mario Kock; Thomas Lindel
Journal:  Chemistry       Date:  2020-09-16       Impact factor: 5.236

Review 8.  Marine Indole Alkaloids.

Authors:  Natalie Netz; Till Opatz
Journal:  Mar Drugs       Date:  2015-08-06       Impact factor: 5.118

9.  Molecular Cloning and Functional Analysis of Gene Clusters for the Biosynthesis of Indole-Diterpenes in Penicillium crustosum and P. janthinellum.

Authors:  Matthew J Nicholson; Carla J Eaton; Cornelia Stärkel; Brian A Tapper; Murray P Cox; Barry Scott
Journal:  Toxins (Basel)       Date:  2015-07-23       Impact factor: 4.546

10.  Study on the synthesis of the cyclopenta[f]indole core of raputindole A.

Authors:  Nils Marsch; Mario Kock; Thomas Lindel
Journal:  Beilstein J Org Chem       Date:  2016-02-23       Impact factor: 2.883
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