| Literature DB >> 1755452 |
J L Simpson1, R H Gray, J T Queenan, R T Kambic, A Pérez, P Mena, M Barbato, F Pardo, G Tagliabue, A Bitto.
Abstract
This international, multicenter, prospective cohort study examines the outcome of pregnancies associated with aging gametes. Comparing pregnancies conceived at or near the peak mucus phase with those occurring before or after the peak provides a means of evaluating the effect of aging gametes. The outcome criteria are (1) rates of spontaneous abortion, (2) low birth weight, and (3) congenital malformations. Preliminary analysis shows a trend toward increased spontaneous abortion with aging gametes in certain subsets (women with prior pregnancy losses) but no effect on birth weight. Too few method failures have yet been studied to make a definitive statement on congenital malformations.Entities:
Keywords: Abortion, Spontaneous; Acceptors; Americas; Biology; Birth Weight; Body Weight; Chile; Cohort Analysis; Colombia; Demographic Factors; Developed Countries; Developing Countries; Diseases; Europe; Family Planning; Family Planning Programs; Family Planning, Behavioral Methods; Fetal Death; Italy; Latin America; Mediterranean Countries; Mortality; Natural Family Planning; North America; Northern America; Peru; Physiology; Population; Population Dynamics; Pregnancy; Pregnancy Complications; Pregnancy Outcomes; Prospective Studies; Reproduction; Research Methodology; Research Report; South America; Southern Europe; Studies; Sympto-thermal Method; Time Factors; United States
Mesh：
Year: 1991 PMID： 1755452 DOI： 10.1016/s0002-9378(11)90557-2
Source DB: PubMed Journal: Am J Obstet Gynecol ISSN： 0002-9378 Impact factor: 8.661