OBJECTIVE: To study the suitability of resorbable polylactides for reconstruction in middle ear surgery. EXPERIMENTAL ANIMALS: Twenty-four chinchillas. INTERVENTIONS: Twenty chinchillas were operated on using 2 types of polylactides inserted into the middle ear and outer ear canal, 10 animals in each group. At 6 months, the animals were killed, and their temporal bones were removed for sectioning. Degree of inflammation, fibrosis, degradation of polylactide material, and new bone formation were assessed histologically. MAIN OUTCOME MEASURES: Polylactide implants caused only a mild local inflammation, with no difference between the 2 materials tested. CONCLUSION: Polylactide acid-based middle ear implants were successfully used in the reconstructive middle ear surgery. Resorption occurred without complications.
OBJECTIVE: To study the suitability of resorbable polylactides for reconstruction in middle ear surgery. EXPERIMENTAL ANIMALS: Twenty-four chinchillas. INTERVENTIONS: Twenty chinchillas were operated on using 2 types of polylactides inserted into the middle ear and outer ear canal, 10 animals in each group. At 6 months, the animals were killed, and their temporal bones were removed for sectioning. Degree of inflammation, fibrosis, degradation of polylactide material, and new bone formation were assessed histologically. MAIN OUTCOME MEASURES: Polylactide implants caused only a mild local inflammation, with no difference between the 2 materials tested. CONCLUSION:Polylactide acid-based middle ear implants were successfully used in the reconstructive middle ear surgery. Resorption occurred without complications.