Literature DB >> 17553680

Antimicrobial activity of rationally designed amino terminal modified peptides.

Gopal Singh Bisht1, Diwan S Rawat, Anil Kumar, Rita Kumar, Santosh Pasha.   

Abstract

Series of short amino terminal modified cationic peptides were designed and synthesized. All of the synthesized compounds were tested against gram-positive as well as gram-negative bacterial strain. Some of the compounds exhibit potent antibacterial activity and no hemolytic activity even at high dose level (1000 microg/mL) in mammalian erythrocytes was observed.

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Year:  2007        PMID: 17553680     DOI: 10.1016/j.bmcl.2007.05.015

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  8 in total

1.  Language models can learn complex molecular distributions.

Authors:  Daniel Flam-Shepherd; Kevin Zhu; Alán Aspuru-Guzik
Journal:  Nat Commun       Date:  2022-06-07       Impact factor: 17.694

2.  Comparative Analysis of the Antimicrobial Activities of Plant Defensin-Like and Ultrashort Peptides against Food-Spoiling Bacteria.

Authors:  Joanna Kraszewska; Michael C Beckett; Tharappel C James; Ursula Bond
Journal:  Appl Environ Microbiol       Date:  2016-06-30       Impact factor: 4.792

Review 3.  The potential of antimicrobial peptides as biocides.

Authors:  Garry Laverty; Sean P Gorman; Brendan F Gilmore
Journal:  Int J Mol Sci       Date:  2011-10-06       Impact factor: 5.923

Review 4.  Evolution of antimicrobial peptides to self-assembled peptides for biomaterial applications.

Authors:  Alice P McCloskey; Brendan F Gilmore; Garry Laverty
Journal:  Pathogens       Date:  2014-10-03

5.  Antimicrobial and Antibiofilm Activity of UP-5, an Ultrashort Antimicrobial Peptide Designed Using Only Arginine and Biphenylalanine.

Authors:  Ammar Almaaytah; Mohammed T Qaoud; Gubran Khalil Mohammed; Ahmad Abualhaijaa; Daniel Knappe; Ralf Hoffmann; Qosay Al-Balas
Journal:  Pharmaceuticals (Basel)       Date:  2018-01-02

Review 6.  Lipidation of Antimicrobial Peptides as a Design Strategy for Future Alternatives to Antibiotics.

Authors:  Taylor Rounds; Suzana K Straus
Journal:  Int J Mol Sci       Date:  2020-12-18       Impact factor: 5.923

7.  Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine.

Authors:  Sílvia Vilà; Esther Badosa; Emilio Montesinos; Marta Planas; Lidia Feliu
Journal:  PLoS One       Date:  2016-03-23       Impact factor: 3.240

8.  Antimalarial activity of ultra-short peptides.

Authors:  Lemuel Pérez-Picaso; Benjamín Velasco-Bejarano; A Berenice Aguilar-Guadarrama; Rocío Argotte-Ramos; María Yolanda Rios
Journal:  Molecules       Date:  2009-12-08       Impact factor: 4.411

  8 in total

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