Literature DB >> 17552408

Use of topical corticosteroids on chronic leg ulcers.

D Hofman1, K Moore, R Cooper, M Eagle, S Cooper.   

Abstract

OBJECTIVE: Topical corticosteroids are widely used in the management of chronic wounds, yet there is little evidence to support this. This pilot study aimed to identify current practice by three specialist nurses and to assess the efficacy of topical corticosteroids.
METHOD: Data on healing, pain relief, exudate reduction and control of hypergranulation tissue were collected on 34 patients whose wounds were treated with topical corticosteroids prospectively in three centres over a three-month period.
RESULTS: Twenty-seven patients (79%) benefited from the application of topical corticosteroid either in terms of healing, pain relief, exudate reduction or the control of hypergranulation tissue. Two wounds deteriorated and treatment was immediately withdrawn.
CONCLUSION: Suppression of inflammation plays an important role in healing and pain relief. Applying topical corticosteroids to the wound can accelerate healing and reduce pain in certain cases. However, careful monitoring is essential as there is a risk of sensitisation with prolonged use as well as a potential increased risk of infection.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17552408     DOI: 10.12968/jowc.2007.16.5.27047

Source DB:  PubMed          Journal:  J Wound Care        ISSN: 0969-0700            Impact factor:   2.072


  12 in total

Review 1.  A review of epidermal maturation arrest: a unique entity or another description of persistent granulation tissue?

Authors:  Maria C Kessides; Amor Khachemoune
Journal:  J Clin Aesthet Dermatol       Date:  2014-12

Review 2.  Wound Healing Concepts in Clinical Practice of OMFS.

Authors:  Shruti Chhabra; Naveen Chhabra; Avneet Kaur; Niti Gupta
Journal:  J Maxillofac Oral Surg       Date:  2016-03-05

3.  An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice.

Authors:  Anca Sindrilaru; Thorsten Peters; Stefan Wieschalka; Corina Baican; Adrian Baican; Henriette Peter; Adelheid Hainzl; Susanne Schatz; Yu Qi; Andrea Schlecht; Johannes M Weiss; Meinhard Wlaschek; Cord Sunderkötter; Karin Scharffetter-Kochanek
Journal:  J Clin Invest       Date:  2011-02-07       Impact factor: 14.808

Review 4.  Factors affecting wound healing.

Authors:  S Guo; L A Dipietro
Journal:  J Dent Res       Date:  2010-02-05       Impact factor: 6.116

Review 5.  Recent technological advances in the management of chronic wounds: A literature review.

Authors:  Benson G Ongarora
Journal:  Health Sci Rep       Date:  2022-05-19

6.  Topical steroids for chronic wounds displaying abnormal inflammation.

Authors:  D C Bosanquet; A Rangaraj; A J Richards; A Riddell; V M Saravolac; K G Harding
Journal:  Ann R Coll Surg Engl       Date:  2013-05       Impact factor: 1.891

Review 7.  The Use of Micro- and Nanocarriers for Resveratrol Delivery into and across the Skin in Different Skin Diseases-A Literature Review.

Authors:  Beata Szulc-Musioł; Beata Sarecka-Hujar
Journal:  Pharmaceutics       Date:  2021-03-26       Impact factor: 6.321

8.  Effect of Vitamin C/Hydrocortisone Immobilization within Curdlan-Based Wound Dressings on In Vitro Cellular Response in Context of the Management of Chronic and Burn Wounds.

Authors:  Michal Wojcik; Paulina Kazimierczak; Vladyslav Vivcharenko; Malgorzata Koziol; Agata Przekora
Journal:  Int J Mol Sci       Date:  2021-10-25       Impact factor: 5.923

9.  Treatment of hypergranulation tissue in burn wounds with topical steroid dressings: a case series.

Authors:  Marie Jaeger; Moti Harats; Rachel Kornhaber; Uri Aviv; Amir Zerach; Josef Haik
Journal:  Int Med Case Rep J       Date:  2016-08-11

10.  Anti-aging pharmacology in cutaneous wound healing: effects of metformin, resveratrol, and rapamycin by local application.

Authors:  Pan Zhao; Bing-Dong Sui; Nu Liu; Ya-Jie Lv; Chen-Xi Zheng; Yong-Bo Lu; Wen-Tao Huang; Cui-Hong Zhou; Ji Chen; Dan-Lin Pang; Dong-Dong Fei; Kun Xuan; Cheng-Hu Hu; Yan Jin
Journal:  Aging Cell       Date:  2017-07-05       Impact factor: 9.304

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.