Literature DB >> 17551754

Six-year stabilisation of a relapsed pelvic mass from rectal cancer after oxaliplatin-containing chemotherapy.

Marco Tampellini1, Maria Pia Brizzi, Raffaella Bitossi, Irene Alabiso, Carla Maria Sculli, Luigi Chiusa, Mauro Papotti, Luigi Dogliotti.   

Abstract

Chemotherapy alone without a multimodality approach has never been demonstrated to cure metastatic colorectal cancer patients. We report the case of a young woman referred in 1999 to our institution for a pelvic relapse of rectal cancer remained stable after oxaliplatin, 5-fluorouracil, and folinic acid therapy and never grown in size up to now, more than 6 years after the last relapse. Death of all the cancer cells, neuroendocrine cells selection, or cell dormancy are some of the discussed explanations to this unique observation. An intriguing question remains open: Should this patient be considered cured?

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Year:  2007        PMID: 17551754     DOI: 10.1007/s00432-007-0234-9

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN: 0171-5216            Impact factor:   4.553


  11 in total

Review 1.  On the growth rates of human malignant tumors: implications for medical decision making.

Authors:  S Friberg; S Mattson
Journal:  J Surg Oncol       Date:  1997-08       Impact factor: 3.454

2.  Five-year survival following hepatic resection after neoadjuvant therapy for nonresectable colorectal.

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Journal:  Ann Surg Oncol       Date:  2001-05       Impact factor: 5.344

Review 3.  Systemic therapy for colorectal cancer.

Authors:  Jeffrey A Meyerhardt; Robert J Mayer
Journal:  N Engl J Med       Date:  2005-02-03       Impact factor: 91.245

4.  Maintenance therapy to suppress micrometastasis: the new challenge for adjuvant cancer treatment.

Authors:  Richard J Epstein
Journal:  Clin Cancer Res       Date:  2005-08-01       Impact factor: 12.531

5.  Liver resection for colorectal metastases.

Authors:  Y Fong; A M Cohen; J G Fortner; W E Enker; A D Turnbull; D G Coit; A M Marrero; M Prasad; L H Blumgart; M F Brennan
Journal:  J Clin Oncol       Date:  1997-03       Impact factor: 44.544

6.  Complete response of colorectal liver metastases after chemotherapy: does it mean cure?

Authors:  Stéphane Benoist; Antoine Brouquet; Christophe Penna; Catherine Julié; Mostafa El Hajjam; Sophie Chagnon; Emmanuel Mitry; Philippe Rougier; Bernard Nordlinger
Journal:  J Clin Oncol       Date:  2006-08-20       Impact factor: 44.544

7.  FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study.

Authors:  Christophe Tournigand; Thierry André; Emmanuel Achille; Gérard Lledo; Michel Flesh; Dominique Mery-Mignard; Emmanuel Quinaux; Corinne Couteau; Marc Buyse; Gérard Ganem; Bruno Landi; Philippe Colin; Christophe Louvet; Aimery de Gramont
Journal:  J Clin Oncol       Date:  2003-12-02       Impact factor: 44.544

8.  Increased endocrine cells in treated rectal adenocarcinomas: a possible reflection of endocrine differentiation in tumor cells induced by chemotherapy and radiotherapy.

Authors:  Jinru Shia; Satish K Tickoo; Jose G Guillem; Jing Qin; Aviram Nissan; Axel Hoos; Alexander Stojadinovic; Leyo Ruo; W Douglas Wong; Philip B Paty; Martin R Weiser; Bruce D Minsky; David S Klimstra
Journal:  Am J Surg Pathol       Date:  2002-07       Impact factor: 6.394

9.  Late relapse and mortality in stage I large bowel cancer.

Authors:  G J Hill; B C Ghosh
Journal:  J Surg Oncol       Date:  1992-09       Impact factor: 3.454

10.  Pulmonary resection for metastases from colorectal cancer: factors influencing prognosis. Twenty-year experience.

Authors:  Ottavio Rena; Caterina Casadio; Franco Viano; Riccardo Cristofori; Enrico Ruffini; Pier Luigi Filosso; Giuliano Maggi
Journal:  Eur J Cardiothorac Surg       Date:  2002-05       Impact factor: 4.191

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  2 in total

1.  Increased neuroendocrine cells in resected metastases compared to primary colorectal adenocarcinomas.

Authors:  Marco Volante; Valerio Marci; Snezana Andrejevic-Blant; Veronica Tavaglione; Maria Carla Sculli; Marco Tampellini; Mauro Papotti
Journal:  Virchows Arch       Date:  2010-09-02       Impact factor: 4.064

2.  Benefit of rebiopsy for deciding treatment strategy in rectal cancer: A case report.

Authors:  Kenta Kawasaki; Yasuo Hamamoto; Takeshi Suzuki; Kenro Hirata; Yasutaka Sukawa; Akiyoshi Kasuga; Yuichiro Hayashi; Hiromasa Takaishi; Kaori Kameyama; Takanori Kanai
Journal:  Oncol Lett       Date:  2017-07-18       Impact factor: 2.967

  2 in total

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