Literature DB >> 17551381

A case of recurrent rash and leg numbness mimicking systemic rheumatic disease: the occurrence of leprosy in a nonendemic area.

Cindy Flower1, David Gaskin, Sean Marquez.   

Abstract

Leprosy, a rare chronic granulomatous communicable disease caused by Mycobacterium leprae, is classically known to have cutaneous and neurologic sequelae. As a result of immigration, the disease, endemic in Brazil, India, Nepal, Madagascar, Myanmar, and Indonesia, has been recognized to be present in North America and the Caribbean. We describe a case of a woman presenting with a long history of a recurrent rash and leg numbness, initially diagnosed with systemic lupus, who was later proven to have lepromatous leprosy. It is a reminder that this underappreciated disease should still be considered in the differential diagnosis of skin rash and neuropathy, even in nonendemic regions.

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Year:  2007        PMID: 17551381     DOI: 10.1097/RHU.0b013e318064e7a0

Source DB:  PubMed          Journal:  J Clin Rheumatol        ISSN: 1076-1608            Impact factor:   3.517


  3 in total

1.  Specific IgG antibody responses may be used to monitor leprosy treatment efficacy and as recurrence prognostic markers.

Authors:  M S Duthie; M N Hay; E M Rada; J Convit; L Ito; L K M Oyafuso; M I P Manini; I M B Goulart; J Lobato; L R Goulart; D Carter; S G Reed
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-05-05       Impact factor: 3.267

2.  Use of protein antigens for early serological diagnosis of leprosy.

Authors:  Malcolm S Duthie; Wakako Goto; Greg C Ireton; Stephen T Reece; Ludimila P V Cardoso; Celina M T Martelli; Mariane M A Stefani; Maria Nakatani; Robson Crusue de Jesus; Eduardo M Netto; Ma V F Balagon; Esterlina Tan; Robert H Gelber; Yumi Maeda; Masahiko Makino; Dan Hoft; Steven G Reed
Journal:  Clin Vaccine Immunol       Date:  2007-09-26

3.  Selection of antigens and development of prototype tests for point-of-care leprosy diagnosis.

Authors:  Malcolm S Duthie; Greg C Ireton; Ganga V Kanaujia; Wakako Goto; Hong Liang; Ajay Bhatia; Jean Marie Busceti; Murdo Macdonald; Kapil Dev Neupane; Chaman Ranjit; Bishwa Raj Sapkota; Marivic Balagon; Javan Esfandiari; Darrick Carter; Steven G Reed
Journal:  Clin Vaccine Immunol       Date:  2008-08-20
  3 in total

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