Literature DB >> 17551075

Screening for Addison's disease in patients with type 1 diabetes mellitus and recurrent hypoglycaemia.

Taruna Likhari1, Saeed Magzoub, Melanie J Griffiths, Harit N Buch, R Gama.   

Abstract

BACKGROUND: Addison's disease may present with recurrent hypoglycaemia in subjects with type 1 diabetes mellitus. There are no data, however, on the prevalence of Addison's disease presenting with recurrent hypoglycaemia in patients with diabetes mellitus.
METHODS: Three year retrospective study of diabetic patients with "unexplained" recurrent hypoglycaemia investigated with a short Synacthen test to exclude adrenocortical insufficiency.
RESULTS: 95 patients with type 1 diabetes mellitus were studied. Addison's disease was identified as the cause of recurrent hypoglycaemia in one patient with type 1 diabetes mellitus.
CONCLUSION: Addison's disease is a relatively rare but remedial cause of recurrent hypoglycaemia in patients with type 1 diabetes mellitus. A low threshold for investigating patients with type 1 diabetes mellitus and recurrent hypoglycaemia to detect Addison's disease is therefore suggested.

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Mesh:

Year:  2007        PMID: 17551075      PMCID: PMC2600050          DOI: 10.1136/pgmj.2007.058321

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  15 in total

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Authors:  George S Eisenbarth; Peter A Gottlieb
Journal:  N Engl J Med       Date:  2004-05-13       Impact factor: 91.245

2.  Autoantibody "subspecificity" in type 1 diabetes: risk for organ-specific autoimmunity clusters in distinct groups.

Authors:  Jennifer M Barker; Jeesuk Yu; Liping Yu; Jian Wang; Dongmei Miao; Fei Bao; Edward Hoffenberg; Jerald C Nelson; Peter A Gottlieb; Marian Rewers; George S Eisenbarth
Journal:  Diabetes Care       Date:  2005-04       Impact factor: 19.112

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Journal:  BMJ       Date:  1996-06-22

5.  A novel presentation of Addison disease: hypoglycemia unawareness in an adolescent with insulin-dependent diabetes mellitus.

Authors:  C Phornphutkul; C M Boney; P A Gruppuso
Journal:  J Pediatr       Date:  1998-05       Impact factor: 4.406

6.  Is a 0900-h serum cortisol useful prior to a short synacthen test in outpatient assessment?

Authors:  C W Le Roux; K Meeran; J Alaghband-Zadeh
Journal:  Ann Clin Biochem       Date:  2002-03       Impact factor: 2.057

7.  Polyglandular autoimmune syndrome type II in patients with idiopathic Addison's disease.

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Journal:  Acta Endocrinol (Copenh)       Date:  1990-04

8.  A treatable cause of recurrent severe hypoglycemia.

Authors:  K J Hardy; M R Burge; P J Boyle; J H Scarpello
Journal:  Diabetes Care       Date:  1994-07       Impact factor: 19.112

9.  Associated autoimmunity in Addison's disease.

Authors:  P M Zelissen; E J Bast; R J Croughs
Journal:  J Autoimmun       Date:  1995-02       Impact factor: 7.094

10.  [Hypoglycemia with loss of consciousness during insulin therapy as an initial symptom of Addison's disease. Report of 2 cases].

Authors:  W Schröter; J Arends; L Runte; A Spelzhaus; H Neumeyer; M Talaulicar; A Boustani; B Willms
Journal:  Dtsch Med Wochenschr       Date:  1985-05-24       Impact factor: 0.628

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Review 3.  Severe Hypoglycemia: Is It Still a Threat for Children and Adolescents With Type 1 Diabetes?

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