Literature DB >> 17550867

Deregulated over expression of FOXP1 protein in diffuse large B-cell lymphoma does not occur as a result of gene rearrangement.

Sharon L Barrans, James A L Fenton, Roland Ventura, Alex Smith, Alison H Banham, Andrew S Jack.   

Abstract

Strong uniform expression of FOXP1 protein occurs in a subgroup of non-germinal centre (GC) diffuse large B-cell lymphomas (DLBCL). We have investigated gene rearrangement as a potential mechanism for deregulated expression of FOXP1 however, using FISH FOXP1 translocations were not found in any case with over-expression of the protein.

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Year:  2007        PMID： 17550867     DOI： 10.3324/haematol.10656

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


  4 in total

1.  Prognostic markers and gene abnormalities in subgroups of diffuse large B-cell lymphoma: single center experience.

Authors:  Petra Korać; Mara Dominis
Journal:  Croat Med J       Date:  2008-10       Impact factor: 1.351

Review 2.  FOXP1: a potential therapeutic target in cancer.

Authors:  Henry B Koon; Gregory C Ippolito; Alison H Banham; Philip W Tucker
Journal:  Expert Opin Ther Targets       Date:  2007-07       Impact factor: 6.902

3.  N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells.

Authors:  Philip J Brown; Duncan M Gascoyne; Linden Lyne; Hayley Spearman; Suet Ling Felce; Nora McFadden; Probir Chakravarty; Sharon Barrans; Steven Lynham; Dinis P Calado; Malcolm Ward; Alison H Banham
Journal:  Haematologica       Date:  2016-04-07       Impact factor: 9.941

4.  Machine Learning-based Classification of Diffuse Large B-cell Lymphoma Patients by Their Protein Expression Profiles.

Authors:  Sally J Deeb; Stefka Tyanova; Michael Hummel; Marc Schmidt-Supprian; Juergen Cox; Matthias Mann
Journal:  Mol Cell Proteomics       Date:  2015-08-26       Impact factor: 5.911
  4 in total

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