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Literature DB >> 1754907

Hemorrhage associated with "bone crisis" in Gaucher's disease identified by magnetic resonance imaging.

Abstract

Children suffering from Gaucher's disease were examined by magnetic resonance imaging (MRI) during a characteristic episode of "bone crisis". An unexpectedly high intramedullary as well as subperiosteal signal was observed on both the T1- and T2-weighted sequences in 5 patients, suggesting a subacute hemorrhage or hematoma. It is conceivable that such a painful hemorrhage is an important component of the "bone crisis" phenomenon. Furthermore, in these cases this is a specific sign which may enable differentiation of bone crises from other types of bone pain associated with Gaucher's disease.

Entities: Disease Species

Mesh：

Year: 1991 PMID： 1754907 DOI： 10.1007/bf00194240

Source DB: PubMed Journal: Skeletal Radiol ISSN： 0364-2348 Impact factor: 2.199

15 in total

1. METABOLISM OF GLUCOCEREBROSIDES. II. EVIDENCE OF AN ENZYMATIC DEFICIENCY IN GAUCHER'S DISEASE.

Authors: R O BRADY; J N KANFER; D SHAPIRO
Journal: Biochem Biophys Res Commun Date: 1965-01-18 Impact factor: 3.575

Review 2. Bone marrow imaging.

Authors: J B Vogler; W A Murphy
Journal: Radiology Date: 1988-09 Impact factor: 11.105

3. Film panel cases Society of Pediatric Radiology. Gaucher's disease with infarction of the tibia and subperiosteal hemorrhage.

Authors:
Journal: Pediatr Radiol Date: 1990

Hemorrhage associated with "bone crisis" in Gaucher's disease identified by magnetic resonance imaging.

1. METABOLISM OF GLUCOCEREBROSIDES. II. EVIDENCE OF AN ENZYMATIC DEFICIENCY IN GAUCHER'S DISEASE.

Review 2. Bone marrow imaging.

3. Film panel cases Society of Pediatric Radiology. Gaucher's disease with infarction of the tibia and subperiosteal hemorrhage.

Review 4. Pseudo-osteomyelitis in Gaucher's disease.

5. Avascular necrosis of the femoral head: early MRI detection and radiological correlation.

6. Gaucher disease: assessment with MR imaging.

7. Composition of the membranous deposits occurring in Gaucher's disease.

8. Demonstration of a deficiency of glucocerebroside-cleaving enzyme in Gaucher's disease.

9. Bone changes in chronic adult Gaucher's disease.

10. Skeletal complications of Gaucher disease.

1. Extraosseous extension caused by epidural hematoma in Gaucher disease mimicking malignant bone tumor.

2. MRI of soft tissue abnormalities: a primary cause of sickle cell crisis.

3. Effective treatment of painful bone crises in type I gaucher's disease with high dose prednisolone.

Review 4. Bone and joint complications related to Gaucher disease.

5. Extraosseous extension of Gaucher cell deposits mimicking malignancy.

6. MR imaging in adults with Gaucher disease type I: evaluation of marrow involvement and disease activity.