Literature DB >> 17548924

[Clinical condition of steroid-induced osteonecrosis of the femoral head].

Toshikazu Kubo1, Mikihiro Fujioka, Masashi Ishida.   

Abstract

Steroid-induced osteonecrosis of the femoral head (steroid-induced ONF) is an aseptic and ischemic disease developing after steroid therapy. Functions of hip joint are markedly disturbed when collapse is developed on the femoral head. Steroid-induced ONF accounted for the majority of the ONF. The occurrence mechanism is unknown, and prevention methods and fundamental remedies remain to be established. The timing of the occurrence of steroid-induced ONF is within several months after steroid administration. During the continuous steroid administration, no expansion of necrotic area was found. Recurrence was not also noticed. Patients have no symptoms when steroid-induced ONF occurs due to the establishment of ischemic conditions, and pain appears when the collapse of femoral head develops. There is an interval of several months or years between the occurrence of ONF and the onset of symptoms. Generally, conservative treatment is chosen during the asymptomatic period, and surgical treatment is considered after the symptoms appear. Appropriate screening and early detection are important to rational remedy for steroid-induced ONF.

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Year:  2007        PMID: 17548924     DOI: CliCa0706856862

Source DB:  PubMed          Journal:  Clin Calcium        ISSN: 0917-5857


  3 in total

1.  Comparative serum proteome expression of the steroid-induced femoral head osteonecrosis in adults.

Authors:  Yuxian Chen; Chun Zeng; Hua Zeng; Rongkai Zhang; Zhiqiang Ye; Bangrong Xing; Kunhua Hu; Mingtao Li; Dao Zhang Cai
Journal:  Exp Ther Med       Date:  2014-11-12       Impact factor: 2.447

2.  Steroid-induced avascular necrosis: A case report on a patient treated with steroid therapy for COVID-19.

Authors:  Gyabina Maharjan; Stuti Yadav; Mandeep Kumar Yadav; Nirajan Khati; Himal Bikram Bhattarai; Jaydev Joshi
Journal:  Ann Med Surg (Lond)       Date:  2022-07-31

3.  MIR31HG polymorphisms are related to steroid-induced osteonecrosis of femoral head among Chinese Han population.

Authors:  Yuan Wang; Yexin Wang; Da Liang; Hongtao Hu; Guangwei Li; Xiaoguang Meng; Bing Zhu; Wei Zhong
Journal:  BMC Musculoskelet Disord       Date:  2022-09-03       Impact factor: 2.562

  3 in total

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