| Literature DB >> 17548492 |
Eric G Solon1, James A Dowell, Jonghui Lee, S Peter King, Bharat D Damle.
Abstract
Penetration of dalbavancin into noninfected bone and joint tissues was assessed after an intravenous dose of 20 mg/kg (of body weight) [(14)C]dalbavancin given to rabbits. Drug-derived radioactivity, determined over 14 days by either liquid scintillation counting or autoradiography, remained above the MIC for common gram-positive pathogens that cause bone and joint infections.Entities:
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Year: 2007 PMID: 17548492 PMCID: PMC1932505 DOI: 10.1128/AAC.00020-07
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191