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Literature DB >> 17546425

Preparation and in vivo investigation of artificial cornea made of nano-hydroxyapatite/poly (vinyl alcohol) hydrogel composite.

Xu Fenglan¹, Li Yubao, Yao Xiaoming, Liao Hongbing, Zhang Li.

Abstract

An artificial cornea consisted of a porous nano-hydroxyapatite/poly (vinyl alcohol) hydrogel (n-HA/PVA-H) skirt and a transparent center poly (vinyl alcohol) hydrogel (PVA-H) were prepared. The n-HA/PVA-H skirt was homogeneously porous and these pores were interconnected. Inter-penetrating network was observed along the interface between the core and the skirt. Artificial corneas were implanted in eyes of rabbit. The corneal tissues were evaluated histological. The results displayed that a good biocompatibility and interlocking had happened between artificial cornea and host tissues. This novel cornea prepared here is potential to be used clinically.

Entities: Chemical Species

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Year: 2007 PMID： 17546425 DOI： 10.1007/s10856-007-2313-5

Source DB: PubMed Journal: J Mater Sci Mater Med ISSN： 0957-4530 Impact factor: 3.896

18 in total

1. Bioceramics: material characteristics versus in vivo behavior.

Authors: P Ducheyne
Journal: J Biomed Mater Res Date: 1987-08

2. Silicone keratoprosthesis.

Authors: A D Ruedemann
Journal: Trans Am Ophthalmol Soc Date: 1974

3. Surface-active biomaterials.

Authors: L L Hench; J Wilson
Journal: Science Date: 1984-11-09 Impact factor: 47.728

4. Results of keratoprosthesis.

Authors: G N Rao; H L Blatt; J V Aquavella
Journal: Am J Ophthalmol Date: 1979-08 Impact factor: 5.258

5. Glaucoma associated with keratoprosthesis.

Authors: P A Netland; H Terada; C H Dohlman
Journal: Ophthalmology Date: 1998-04 Impact factor: 12.079

6. Development of a newly designed double-fixed Seoul-type keratoprosthesis.

Authors: J H Lee; W R Wee; E S Chung; H Y Kim; S H Park; Y H Kim
Journal: Arch Ophthalmol Date: 2000-12

Review 7. An overview of the development of artificial corneas with porous skirts and the use of PHEMA for such an application.

Authors: T V Chirila
Journal: Biomaterials Date: 2001-12 Impact factor: 12.479

8. Poly(vinyl alcohol) hydrogels as soft contact lens material.

Authors: S H Hyon; W I Cha; Y Ikada; M Kita; Y Ogura; Y Honda
Journal: J Biomater Sci Polym Ed Date: 1994 Impact factor: 3.517

9. Osteo-odonto-keratoprosthesis. Description of surgical technique with results in 85 patients.

Authors: V Marchi; R Ricci; I Pecorella; A Ciardi; U Di Tondo
Journal: Cornea Date: 1994-03 Impact factor: 2.651

10. Keratoprosthesis with biocolonizable microporous fluorocarbon haptic. Preliminary results in a 24-patient study.

Authors: J M Legeais; G Renard; J M Parel; M Savoldelli; Y Pouliquen
Journal: Arch Ophthalmol Date: 1995-06

8 in total

Review 1. Problem of hydroxyapatite dispersion in polymer matrices: a review.

Authors: Monika Supová
Journal: J Mater Sci Mater Med Date: 2009-02-20 Impact factor: 3.896

Review 2. Biocomposites and hybrid biomaterials based on calcium orthophosphates.

Authors: Sergey V Dorozhkin
Journal: Biomatter Date: 2011 Jul-Sep

3. Property-based design: optimization and characterization of polyvinyl alcohol (PVA) hydrogel and PVA-matrix composite for artificial cornea.

Authors: Hong Jiang; Yi Zuo; Li Zhang; Jidong Li; Aiming Zhang; Yubao Li; Xiaochao Yang
Journal: J Mater Sci Mater Med Date: 2014-01-25 Impact factor: 3.896

Review 4. Biologic keratoprosthesis materials.

Authors: Joseph B Ciolino; Claes H Dohlman
Journal: Int Ophthalmol Clin Date: 2009