Literature DB >> 17545716

Transmission of multidrug-resistant HIV-1: 5 years of immunological and virological survey.

Constance Delaugerre1, Anne-Genevieve Marcelin, Cathia Soulié, Marie-Laure Chaix, Christine Katlama, Pierre-Marie Girard, Vincent Calvez, Laurence Morand-Joubert.   

Abstract

Multidrug resistant HIV-1 acquired at the time of primary infection in two patients persisted for at least 5 years with and without treatment. In each patient, only one back mutation to wild-type codon in the protease gene occurred, and that was concomitantly associated with a marked CD4 cell count decrease. In both cases, infection was caused by CCR5 viruses and no rapid clinical progression to AIDS after primary infection was observed.

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Year:  2007        PMID： 17545716     DOI： 10.1097/QAD.0b013e3280d6edf1

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  2 in total

1.  Perinatal acquisition of drug-resistant HIV-1 infection: mechanisms and long-term outcome.

Authors:  Constance Delaugerre; Marie-Laure Chaix; Stephane Blanche; Josiane Warszawski; Dorine Cornet; Catherine Dollfus; Veronique Schneider; Marianne Burgard; Albert Faye; Laurent Mandelbrot; Roland Tubiana; Christine Rouzioux
Journal:  Retrovirology       Date:  2009-09-19       Impact factor: 4.602

2.  X4 tropic multi-drug resistant quasi-species detected at the time of primary HIV-1 infection remain exclusive or at least dominant far from PHI.

Authors:  Jade Ghosn; Julie Galimand; Stéphanie Raymond; Laurence Meyer; Christiane Deveau; Cécile Goujard; Jacques Izopet; Christine Rouzioux; Marie-Laure Chaix
Journal:  PLoS One       Date:  2011-08-24       Impact factor: 3.240
  2 in total

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