| Literature DB >> 17543498 |
Varsha K Khodiyar1, Lois J Maltais, Barbara J Ruef, Katherine M B Sneddon, Jennifer R Smith, Mary Shimoyama, Fernando Cabral, Charles Dumontet, Susan K Dutcher, Robert J Harvey, Laurence Lafanechère, John M Murray, Eva Nogales, David Piquemal, Fabio Stanchi, Sue Povey, Ruth C Lovering.
Abstract
An essential component of microtubules, alpha-tubulin is also a multigene family in many species. An orthology-based nomenclature for this gene family has previously been difficult to assign due to incomplete genome builds and the high degree of sequence similarity between members of this family. Using the current genome builds, sequence analysis of human, mouse, and rat alpha-tubulin genes has enabled an updated nomenclature to be generated. This revised nomenclature provides a unified language for the discussion of these genes in mammalian species; it has been approved by the gene nomenclature committees of the three species and is supported by researchers in the field.Entities:
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Year: 2007 PMID： 17543498 DOI： 10.1016/j.ygeno.2007.04.008
Source DB: PubMed Journal: Genomics ISSN： 0888-7543 Impact factor: 5.736