Literature DB >> 17541611

Intra-articular hip viscosupplementation with synthetic hyaluronic acid for osteoarthritis: efficacy, safety and relation to pre-injection radiographs.

M S Gaston1, C H Tiemessen, J E Philips.   

Abstract

OBJECTIVE: The aim of this study was to determine the efficacy and safety of viscosupplementation with synthetic hyaluronic acid to the hip joint and to determine if there was any relation to pre-injection radiographic changes of osteoarthritis (OA).
METHODS: Three Suplasyn injections were performed each to 15 hips with OA. Standing antero-posterior radiographs of the pelvis were performed prior to injection and scored according to Kelgren and Lawrence grades along with recordings of the minimum joint space width. Harris Hip Scores (HHS) which contain a component for pain, function, activities, absence of deformity and range of motion were recorded pre-injection and at 3 and 6 months.
RESULTS: We established that at 3 months the HHS is significantly higher (P < 0.05). At 6 months, four hips had been excluded as they has went on to total hip arthroplasty (these hips showed a lower HHS at 3 months). For the remaining hips the HHS was highly significantly increased (P < 0.001). No side effects or complications were observed. Analysis of the pre-injection radiographs showed a trend towards a bigger increase in HHS with less radiographic OA changes.
CONCLUSIONS: Viscosupplementation performed under fluoroscopic guidance is an effective and safe method of treating hip OA and appears to be more efficacious in those with less radiographic changes of OA.

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Year:  2007        PMID: 17541611     DOI: 10.1007/s00402-007-0363-2

Source DB:  PubMed          Journal:  Arch Orthop Trauma Surg        ISSN: 0936-8051            Impact factor:   3.067


  6 in total

1.  Viscosupplementation with intra-articular hyaluronic acid for hip disorders. A systematic review and meta-analysis.

Authors:  Eleonora Piccirilli; Francesco Oliva; Mihaela Aconstantinesei Murè; Asmaa Mahmoud; Calogero Foti; Umberto Tarantino; Nicola Maffulli
Journal:  Muscles Ligaments Tendons J       Date:  2016-12-21

Review 2.  The role of intra-articular hyaluronan (Sinovial) in the treatment of osteoarthritis.

Authors:  Antonio Gigante; Leonardo Callegari
Journal:  Rheumatol Int       Date:  2010-11-28       Impact factor: 2.631

3.  Effects of medications on incidence and risk of knee and hip joint replacement in patients with osteoarthritis: a systematic review and meta-analysis.

Authors:  Beibei Cui; Yuehong Chen; Yunru Tian; Huan Liu; Yupeng Huang; Geng Yin; Qibing Xie
Journal:  Adv Rheumatol       Date:  2022-06-27

Review 4.  Viscosupplementation for hip osteoarthritis: Does systematic review of patient-reported outcome measures support use?

Authors:  Alexander J Acuña; Linsen T Samuel; Stacy H Jeong; Ahmed K Emara; Atul F Kamath
Journal:  J Orthop       Date:  2020-03-25

5.  Prognostic factors after intra-articular hyaluronic acid injection in ankle osteoarthritis.

Authors:  Seung Hwan Han; Do Young Park; Tae Hun Kim
Journal:  Yonsei Med J       Date:  2014-07       Impact factor: 2.759

Review 6.  Recent advances in hyaluronic acid based therapy for osteoarthritis.

Authors:  Steven Bowman; Mohamed E Awad; Mark W Hamrick; Monte Hunter; Sadanand Fulzele
Journal:  Clin Transl Med       Date:  2018-02-16
  6 in total

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