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Comparison of 99Tcm-HMPAO-labelled white blood cells and 67Ga citrate scans to detect myocarditis in the acute phase of Kawasaki disease.

C H Kao¹, K S Hsieh, Y L Wang, C W Chen, S Q Liao, S J Wang, S H Yeh.

Abstract

Myocardial imaging with 99Tcm-HMPAO-labelled white blood cells (WBC) and 67Ga citrate was used to detect myocarditis in the acute phase of Kawasaki disease among 22 infants and children; 18 cases of myocarditis were detected by 99Tcm-HMPAO-labelled WBC heart scans, but only one case was detected by 67Ga citrate heart scans. In conclusion, 99Tcm-HMPAO-labelled WBC scanning provides a more sensitive method than 67Ga citrate scanning in the detection of myocarditis in Kawasaki disease.

Entities: Chemical Disease Species

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Year: 1991 PMID： 1754155 DOI： 10.1097/00006231-199111000-00004

Source DB: PubMed Journal: Nucl Med Commun ISSN： 0143-3636 Impact factor: 1.690

Comparison of 99Tcm-HMPAO-labelled white blood cells and 67Ga citrate scans to detect myocarditis in the acute phase of Kawasaki disease.

1. The use of technetium-99m hexamethylpropylene amine oxime labelled white blood cells to detect subclinical inflammation of the heart after cardiopulmonary bypass in children with congenital heart disease.

2. Clinical value of gallium-67 scintigraphy in assessment of disease activity in Wegener's granulomatosis.

3. Relationships between coronary artery dilatation and severity of carditis detected by two-dimensional echocardiography and [99mTc]HMPAO-labeled white blood cell heart scan in children with Kawasaki disease.