Literature DB >> 17541202

Two new xanthones isolated from the stem bark of Garcinia lancilimba.

Nian-Yun Yang1, Quan-Bin Han, Xin-Wei Cao, Chun-Feng Qiao, Jing-Zheng Song, Shi-Lin Chen, Da-Jian Yang, Hillary Yiu, Hong-Xi Xu.   

Abstract

Two new xanthones, 1,5,6-trihydroxy-6',6'-dimethyl-2H-pyrano(2',3':3,4)-2-(3-methylbut-2-enyl)xanthone (1) and 1,6,7-trihydroxy-6',6'-dimethyl-2H-pyrano(2',3':3,2)-4-(3-methylbut-2-enyl)xanthone (2), have been isolated from the stem bark of Garcinia lancilimba (Guttiferae), together with six known xanthones. Their structures were identified on the basis of extensive spectral evidence including detailed 2D NMR and HR-MS data. Two new compounds showed moderate inhibitory effect on human breast cancer MDA-MB-435S cell line.

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Year:  2007        PMID: 17541202     DOI: 10.1248/cpb.55.950

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  3 in total

1.  Three new xanthones from the leaves of Garcinia lancilimba.

Authors:  Yating Sun; Dahong Li; Cuicui Jia; Chunmei Xue; Jiao Bai; Zhanlin Li; Huiming Hua
Journal:  J Nat Med       Date:  2015-12-08       Impact factor: 2.343

2.  Hypericum species in the Páramos of Central and South America: a special focus upon H. irazuense Kuntze ex N. Robson.

Authors:  Sara Crockett; Marianne Eberhardt; Olaf Kunert; Wolfgang Schühly
Journal:  Phytochem Rev       Date:  2010-06       Impact factor: 5.374

3.  Anti-Tumor Xanthones from Garcinia nujiangensis Suppress Proliferation, and Induce Apoptosis via PARP, PI3K/AKT/mTOR, and MAPK/ERK Signaling Pathways in Human Ovarian Cancers Cells.

Authors:  Zhongyan Tang; Lihua Lu; Zhengxiang Xia
Journal:  Drug Des Devel Ther       Date:  2020-09-25       Impact factor: 4.162

  3 in total

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