Literature DB >> 17540483

Cloning of full length genome of varicella-zoster virus vaccine strain into a bacterial artificial chromosome and reconstitution of infectious virus.

Hironori Yoshii1, Pranee Somboonthum, Michiaki Takahashi, Koichi Yamanishi, Yasuko Mori.   

Abstract

The complete genome of the varicella-zoster virus (VZV) Oka vaccine strain (vOka) has been cloned into a bacterial artificial chromosome (BAC), and several BAC clones with the vOka genome have been obtained. Infectious viruses were reconstituted in MRC-5 cells transfected with the vOka-BAC DNA clones. The clones were distributed into two groups based on differences in amino acids found in ORF 62/71 region among the vOka-BAC clones. The recombinant vOka (rvOka) grew slower than recombinant Oka parental virus (rpOka), pOka and vOka. This is the first report that the vOka genome was cloned into BAC vector. The rvOka-BAC system would be useful as a vector for construction of recombinant live vaccines.

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Year:  2007        PMID： 17540483     DOI： 10.1016/j.vaccine.2007.04.064

Source DB:  PubMed          Journal:  Vaccine        ISSN： 0264-410X            Impact factor:   3.641


  15 in total

Review 1.  Recent advances in cloning herpesviral genomes as infectious bacterial artificial chromosomes.

Authors:  Fuchun Zhou; Shou-Jiang Gao
Journal:  Cell Cycle       Date:  2011-02-01       Impact factor: 4.534

2.  Cloning the simian varicella virus genome in E. coli as an infectious bacterial artificial chromosome.

Authors:  Wayne L Gray; Fuchun Zhou; Juliane Noffke; B Karsten Tischer
Journal:  Arch Virol       Date:  2011-04-13       Impact factor: 2.574

3.  A herpes simplex virus 2 glycoprotein D mutant generated by bacterial artificial chromosome mutagenesis is severely impaired for infecting neuronal cells and infects only Vero cells expressing exogenous HVEM.

Authors:  Kening Wang; Justin D Kappel; Caleb Canders; Wilmer F Davila; Dean Sayre; Mayra Chavez; Lesley Pesnicak; Jeffrey I Cohen
Journal:  J Virol       Date:  2012-09-19       Impact factor: 5.103

Review 4.  The varicella-zoster virus genome.

Authors:  Jeffrey I Cohen
Journal:  Curr Top Microbiol Immunol       Date:  2010       Impact factor: 4.291

5.  Varicella zoster virus latency.

Authors:  Emily Eshleman; Aamir Shahzad; Randall J Cohrs
Journal:  Future Virol       Date:  2011-03       Impact factor: 1.831

6.  Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu mice.

Authors:  Jenny Rowe; Rebecca J Greenblatt; Dongmei Liu; Jennifer F Moffat
Journal:  Antiviral Res       Date:  2010-03-20       Impact factor: 5.970

7.  Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome contains a duplication of a long unique-region fragment within the terminal repeat region.

Authors:  Yuri Yakushko; Christian Hackmann; Thomas Günther; Jessica Rückert; Marc Henke; Lars Koste; Khaled Alkharsah; Jens Bohne; Adam Grundhoff; Thomas F Schulz; Cornelia Henke-Gendo
Journal:  J Virol       Date:  2011-02-09       Impact factor: 5.103

8.  Autoexcision of bacterial artificial chromosome facilitated by terminal repeat-mediated homologous recombination: a novel approach for generating traceless genetic mutants of herpesviruses.

Authors:  Fuchun Zhou; Qiuhua Li; Scott W Wong; Shou-Jiang Gao
Journal:  J Virol       Date:  2010-01-13       Impact factor: 5.103

9.  Human herpesvirus 6 major immediate early promoter has strong activity in T cells and is useful for heterologous gene expression.

Authors:  Masaaki Matsuura; Masaya Takemoto; Koichi Yamanishi; Yasuko Mori
Journal:  Virol J       Date:  2011-01-11       Impact factor: 4.099

10.  Recombinant varicella-zoster virus vaccines as platforms for expression of foreign antigens.

Authors:  Wayne L Gray
Journal:  Adv Virol       Date:  2013-06-13
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