| Literature DB >> 17539946 |
K H Scheuer1, K Svenstrup, P Jennum, B á Rogvi-Hansen, L Werdelin, K Fenger, J E Nielsen.
Abstract
Patients with hereditary spastic paraplegia (HSP) are often treated with antispastic drugs to relieve symptoms but documentation is lacking. In this study, gabapentin was tested in a double-blind crossover trial on a group of patients with HSP and linkage to the SPG4 locus. There was no difference between periods with gabapentin and placebo treatment in clinical assessment, self-reported parameters or paired transcranial magnetic stimulation evaluation of motor cortical excitability.Entities:
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Year: 2007 PMID： 17539946 DOI： 10.1111/j.1468-1331.2007.01812.x
Source DB: PubMed Journal: Eur J Neurol ISSN： 1351-5101 Impact factor: 6.089