Literature DB >> 17539671

Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum.

María Pardo1, Angel García, Robin Antrobus, María José Blanco, Raymond A Dwek, Nicole Zitzmann.   

Abstract

There is a necessity to better characterize uveal melanoma (UM) tumors according to their metastasis potential at an early stage. In this study we report the identification of potential biomarkers by a combination of proteomics-related approaches: the characterization of UM cell secretomes, the analysis of UM autoantibodies, and the differential depleted serum proteome analysis. We describe a possible role of cathepsin D, syntenin, and gp100 in UM as potential biomarkers.

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Year:  2007        PMID： 17539671     DOI： 10.1021/pr070021t

Source DB:  PubMed          Journal:  J Proteome Res        ISSN： 1535-3893            Impact factor:   4.466


  20 in total

1.  Computational prediction of human proteins that can be secreted into the bloodstream.

Authors:  Juan Cui; Qi Liu; David Puett; Ying Xu
Journal:  Bioinformatics       Date:  2008-08-12       Impact factor: 6.937

Review 2.  Plasma membrane proteomics and its application in clinical cancer biomarker discovery.

Authors:  Rikke Leth-Larsen; Rikke R Lund; Henrik J Ditzel
Journal:  Mol Cell Proteomics       Date:  2010-04-08       Impact factor: 5.911

3.  Characterization of extracellular vesicles isolated from different liquid biopsies of uveal melanoma patients.

Authors:  Carmen Luz Pessuti; Deise Fialho Costa; Kleber S Ribeiro; Mohamed Abdouh; Thupten Tsering; Heloisa Nascimento; Alessandra G Commodaro; Allexya Affonso Antunes Marcos; Ana Claudia Torrecilhas; Rubens N Belfort; Rubens Belfort; Julia Valdemarin Burnier
Journal:  J Circ Biomark       Date:  2022-06-27

Review 4.  Cancer and the tumor microenvironment: a review of an essential relationship.

Authors:  Flaubert Mbeunkui; Donald J Johann
Journal:  Cancer Chemother Pharmacol       Date:  2008-12-14       Impact factor: 3.333

Review 5.  Blood biomarkers for uveal melanoma.

Authors:  Pierre L Triozzi; Arun D Singh
Journal:  Future Oncol       Date:  2012-02       Impact factor: 3.674

6.  New approaches for biomarker discovery: the search for liver fibrosis markers in hepatitis C patients.

Authors:  Bevin Gangadharan; Robin Antrobus; David Chittenden; Jan Rossa; Manisha Bapat; Paul Klenerman; Eleanor Barnes; Raymond A Dwek; Nicole Zitzmann
Journal:  J Proteome Res       Date:  2011-03-30       Impact factor: 4.466

Review 7.  Targeting tumor invasion: the roles of MDA-9/Syntenin.

Authors:  Timothy P Kegelman; Swadesh K Das; Luni Emdad; Bin Hu; Mitchell E Menezes; Praveen Bhoopathi; Xiang-Yang Wang; Maurizio Pellecchia; Devanand Sarkar; Paul B Fisher
Journal:  Expert Opin Ther Targets       Date:  2014-09-15       Impact factor: 6.902

8.  FNDC5/irisin is not only a myokine but also an adipokine.

Authors:  Arturo Roca-Rivada; Cecilia Castelao; Lucía L Senin; María O Landrove; Javier Baltar; Ana Belén Crujeiras; Luisa María Seoane; Felipe F Casanueva; María Pardo
Journal:  PLoS One       Date:  2013-04-11       Impact factor: 3.240

9.  Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.

Authors:  Bevin Gangadharan; Manisha Bapat; Jan Rossa; Robin Antrobus; David Chittenden; Bettina Kampa; Eleanor Barnes; Paul Klenerman; Raymond A Dwek; Nicole Zitzmann
Journal:  PLoS One       Date:  2012-06-26       Impact factor: 3.240

Review 10.  The cancer secretome: a reservoir of biomarkers.

Authors:  Hua Xue; Bingjian Lu; Maode Lai
Journal:  J Transl Med       Date:  2008-09-17       Impact factor: 5.531
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