Literature DB >> 17539193

Costs of community-acquired pediatric rotavirus gastroenteritis in 7 European countries: the REVEAL Study.

Carlo Giaquinto1, Pierre Van Damme, Frédéric Huet, Leif Gothefors, Marie Van der Wielen.   

Abstract

BACKGROUND: Morbidity and resource use due to rotavirus gastroenteritis (RVGE) are substantial in Europe, although comprehensive data on the economic impact of the disease are lacking.
METHODS: A cost study was conducted to assess health care resource use data collected during a prospective epidemiologic study of acute gastroenteritis in children <5 years of age in selected areas of Belgium, France, Germany, Italy, Spain, Sweden, and the United Kingdom. We calculated the average cost (direct and indirect) per episode of confirmed RVGE in primary care, emergency department, and hospital settings.
RESULTS: The total societal cost (including direct medical, direct nonmedical, and indirect costs) per episode of RVGE ranged from 166 euros to 473 euros in the primary care setting, from 334 euros to 770 euros in the emergency department setting, and from 1525 euros to 2101 euros in the hospital setting. The majority of hospital-related costs were reimbursed by national health care payers, but the percentage of reimbursed costs declined progressively in the emergency department and primary care settings. The mean number of workdays lost by parents and other relatives varied between study areas and settings, ranging from 2.3 to 7.5 days, and this represented the major cost not reimbursed by national health care payers.
CONCLUSIONS: RVGE incurs considerable resource utilization in all health care settings and substantial costs for national health care payers, families of patients, and employers. Routine rotavirus vaccination in infants could significantly reduce the health and economic burden of pediatric RVGE.

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Mesh:

Year:  2007        PMID: 17539193     DOI: 10.1086/516716

Source DB:  PubMed          Journal:  J Infect Dis        ISSN: 0022-1899            Impact factor:   5.226


  38 in total

1.  Cost-effectiveness of rotavirus vaccination in Bolivia from the state perspective.

Authors:  Emily R Smith; Emily E Rowlinson; Volga Iniguez; Kizee A Etienne; Rosario Rivera; Nataniel Mamani; Rick Rheingans; Maritza Patzi; Percy Halkyer; Juan S Leon
Journal:  Vaccine       Date:  2011-09-02       Impact factor: 3.641

Review 2.  Burden of rotavirus gastroenteritis in the pediatric population in Central and Eastern Europe: serotype distribution and burden of illness.

Authors:  Isla Ogilvie; Hanane Khoury; Antoine C El Khoury; Mireille M Goetghebeur
Journal:  Hum Vaccin       Date:  2011-05-01

3.  Decline in rotavirus hospitalizations following the first three years of vaccination in Castile-La Mancha, Spain.

Authors:  Olga Redondo; Rosa Cano; Lorena Simón
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

Review 4.  Rotavirus infections and vaccines: burden of illness and potential impact of vaccination.

Authors:  Keith Grimwood; Stephen B Lambert; Richard J Milne
Journal:  Paediatr Drugs       Date:  2010-08-01       Impact factor: 3.022

5.  Disease burden of enterovirus 71 in rural central China: A community-based survey.

Authors:  Zheng-kai Gan; Hui Jin; Jing-xin Li; Xue-jun Yao; Yang Zhou; Xue-feng Zhang; Feng-cai Zhu
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

6.  Impact of community-acquired paediatric rotavirus gastroenteritis on family life: data from the REVEAL study.

Authors:  Marie Van der Wielen; Carlo Giaquinto; Leif Gothefors; Christel Huelsse; Frédéric Huet; Martina Littmann; Melanie Maxwell; José M P Talayero; Peter Todd; Miguel T Vila; Luigi Cantarutti; Pierre Van Damme
Journal:  BMC Fam Pract       Date:  2010-03-15       Impact factor: 2.497

7.  Burden of paediatric Rotavirus Gastroenteritis (RVGE) and potential benefits of a universal Rotavirus vaccination programme with a pentavalent vaccine in Spain.

Authors:  Javier Diez-Domingo; Nuria Lara Suriñach; Natalia Malé Alcalde; Lourdes Betegón; Nathalie Largeron; Mélanie Trichard
Journal:  BMC Public Health       Date:  2010-08-10       Impact factor: 3.295

8.  Temperature-dependent transmission of rotavirus in Great Britain and The Netherlands.

Authors:  C J Atchison; C C Tam; S Hajat; W van Pelt; J M Cowden; B A Lopman
Journal:  Proc Biol Sci       Date:  2009-11-25       Impact factor: 5.349

9.  Impact of rotavirus vaccination in regions with low and moderate vaccine uptake in Germany.

Authors:  Sandra Dudareva-Vizule; Judith Koch; Matthias An der Heiden; Doris Oberle; Brigitte Keller-Stanislawski; Ole Wichmann
Journal:  Hum Vaccin Immunother       Date:  2012-09-07       Impact factor: 3.452

10.  The Economic Value of Vaccination: Why Prevention is Wealth.

Authors: 
Journal:  J Mark Access Health Policy       Date:  2015-08-12
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