| Literature DB >> 17537590 |
O Parant1, S Grandjean, R Castagno, B Letourneur, R Desprats, V Larrue.
Abstract
Familial hypokalemic periodic paralysis (FHPP) is a rare inherited disease characterized by a dysfunction of the membrane ion channels. Clinical manifestations are attacks of hypokaliemia with flaccid muscle paralysis. Paralysis is sometimes severe but always reversible with symptomatic treatment. Pregnancy and delivery have been reported to exacerbate FHPP. Authors report a case of FHPP during pregnancy with a favourable outcome. Vaginal delivery is usually possible with monitoring and epidural analgesia, avoiding active maternal expulsive efforts (passive descent of the fetus and elective outlet forceps) and other stimulating factors (carbohydrate loads, maternal stress, betamimetics, epinephrine...). Administration of IV potassium supplementation is often necessary.Entities:
Mesh:
Year: 2007 PMID: 17537590 DOI: 10.1016/j.jgyn.2007.04.009
Source DB: PubMed Journal: J Gynecol Obstet Biol Reprod (Paris) ISSN: 0150-9918