Literature DB >> 17535610

Impact of HIV and AIDS on surgical practice.

R S Dua1, S A Wajed, M C Winslet.   

Abstract

INTRODUCTION: Surgical intervention has become a common component in the management of patients infected with the human immunodeficiency virus (HIV) or suffering from the clinical consequences of acquired immunodeficiency syndrome (AIDS). We investigated the evolution of this involvement at a tertiary referral centre for this condition over a 16-year period. PATIENTS AND METHODS: Detailed retrospective examination of the medical records of HIV-positive patients treated at the Royal Free Hospital between 1986 and 2002 was undertaken. Clinical, pathological and operative details of those patients who underwent surgical intervention were recorded.
RESULTS: Of the 2100 cases reviewed, 477 patients underwent a combined total of 772 surgical procedures. Of the 772 operations, 95 (12.3%) were performed as emergencies. Anorectal surgery represented the highest group with a total of 195 procedures (25.26%) being undertaken. The majority of patients (59%) had AIDS at the time of surgery, and 27.04% had a significant co-existing medical problem. Overall postoperative complication rate was 10.1%, with the risk being significantly greater in those undergoing intra-abdominal surgery and emergency procedures.
CONCLUSIONS: This is the largest study to audit the impact of HIV/AIDS in general surgical practice in the UK retrospectively. Surgery for HIV patients can be safely conducted with a low complication rate for the diagnostic and anorectal procedures that comprise the vast majority of surgery in HIV/AIDS patients. Medical treatment for patients with HIV/AIDS has developed dramatically over the last two decades. In parallel, this has resulted in a heavy, new and varied workload for general surgeons, who have also had to adapt in order to deal with the challenging spectrum of this disease.

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Year:  2007        PMID: 17535610      PMCID: PMC1963606          DOI: 10.1308/003588407X183436

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  7 in total

1.  Post-cesarean section morbidity in HIV-positive women.

Authors:  V Maiques-Montesinos; J Cervera-Sanchez; J Bellver-Pradas; A Abad-Carrascosa; V Serra-Serra
Journal:  Acta Obstet Gynecol Scand       Date:  1999-10       Impact factor: 3.636

2.  Prospective study of healing time after hemorrhoidectomy: influence of HIV infection, acquired immunodeficiency syndrome, and anal wound infection.

Authors:  E Morandi; D Merlini; A Salvaggio; D Foschi; E Trabucchi
Journal:  Dis Colon Rectum       Date:  1999-09       Impact factor: 4.585

3.  Human immunodeficiency virus and the trauma patient: factors influencing postoperative infectious complications.

Authors:  A A Guth; S R Hofstetter; H L Pachter
Journal:  J Trauma       Date:  1996-08

4.  Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators.

Authors:  F J Palella; K M Delaney; A C Moorman; M O Loveless; J Fuhrer; G A Satten; D J Aschman; S D Holmberg
Journal:  N Engl J Med       Date:  1998-03-26       Impact factor: 91.245

5.  Abdominal pain in the HIV infected patient.

Authors:  Douglas Yoshida; J Michael Caruso
Journal:  J Emerg Med       Date:  2002-08       Impact factor: 1.484

6.  1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults.

Authors: 
Journal:  MMWR Recomm Rep       Date:  1992-12-18

7.  Appendicitis in HIV-positive patients.

Authors:  R Bova; A Meagher
Journal:  Aust N Z J Surg       Date:  1998-05
  7 in total
  17 in total

1.  CD4 Count is Still a Valid Indicator of Outcome in HIV-Infected Patients Undergoing Major Abdominal Surgery in the Era of Highly Active Antiretroviral Therapy.

Authors:  A Chichom-Mefire; M Azabji-Kenfack; J Atashili
Journal:  World J Surg       Date:  2015-07       Impact factor: 3.352

2.  Clinical Profile of Surgical Diseases with Emergence of New Problems in HIV+ Individuals.

Authors:  Tejaswini Vallabha; Mandar Dhamangaonkar; Vikram Sindgikar; Ravindra Nidoni; Harshavardhan Biradar; Aniketan Kv; Ramakant Baloorkar
Journal:  Indian J Surg       Date:  2016-01-25       Impact factor: 0.656

3.  Trends and causes of hospitalizations among HIV-infected persons during the late HAART era: what is the impact of CD4 counts and HAART use?

Authors:  Nancy F Crum-Cianflone; Greg Grandits; Sara Echols; Anuradha Ganesan; Michael Landrum; Amy Weintrob; Robert Barthel; Brian Agan
Journal:  J Acquir Immune Defic Syndr       Date:  2010-07       Impact factor: 3.731

Review 4.  Human immunodeficiency disease: how should it affect surgical decision making?

Authors:  T E Madiba; D J J Muckart; S R Thomson
Journal:  World J Surg       Date:  2009-05       Impact factor: 3.352

5.  Colorectal Surgery in Patients with HIV and AIDS: Trends and Outcomes over a 10-Year Period in the USA.

Authors:  John V Gahagan; Wissam J Halabi; Vinh Q Nguyen; Joseph C Carmichael; Alessio Pigazzi; Michael J Stamos; Steven D Mills
Journal:  J Gastrointest Surg       Date:  2016-03-03       Impact factor: 3.452

6.  The Effect of Human-Immunodeficiency Virus Status on Outcomes in Penetrating Abdominal Trauma: An Interim Analysis.

Authors:  Deidre McPherson; Valentin Neuhaus; Rohin Dhar; Sorin Edu; Andrew J Nicol; Pradeep H Navsaria
Journal:  World J Surg       Date:  2018-08       Impact factor: 3.352

Review 7.  Perianal infections: a primer for nonsurgeons.

Authors:  Masood Mansour; Lynn A Weston
Journal:  Curr Gastroenterol Rep       Date:  2010-08

8.  HIV, appendectomy and postoperative complications at a reference hospital in Northwest Tanzania: cross-sectional study.

Authors:  Geofrey C Giiti; Humphrey D Mazigo; Jorg Heukelbach; William Mahalu
Journal:  AIDS Res Ther       Date:  2010-12-29       Impact factor: 2.250

9.  Perioperative Antiretroviral Regimen for HIV/AIDS Patients Who Underwent Abdominal Surgery.

Authors:  Jing Yang; Guo Wei; Yong He; Xin Hua; Shifeng Feng; Yong Zhao; Tingyu Chen; Hua Wang; Liang Guo
Journal:  World J Surg       Date:  2020-06       Impact factor: 3.282

10.  Effect of emergency major abdominal surgery on CD4 cell count among HIV positive patients in a sub-Saharan Africa tertiary hospital--a prospective study.

Authors:  Gabriel Okumu; Patson Makobore; Sam Kaggwa; Andrew Kambugu; Moses Galukande
Journal:  BMC Surg       Date:  2013-02-26       Impact factor: 2.102

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