Literature DB >> 17534697

CTRP3/cartducin promotes proliferation and migration of endothelial cells.

Hironori Akiyama1, Souhei Furukawa, Satoshi Wakisaka, Takashi Maeda.   

Abstract

CTRP3/cartducin, a novel secretory protein, is a member of the C1q and tumor necrosis factor (TNF)-related protein (CTRP) superfamily. CTRP3/cartducin gene is transiently up-regulated in a balloon-injured rat carotid artery tissue. In this study, we report a new function of CTRP3/cartducin as a regulator of angiogenic processes. CTRP3/cartducin promoted proliferation and migration of mouse endothelial MSS31 cells in a dose-dependent manner. Further, stimulation of MSS31 by CTRP3/cartducin led to activation of extracellular signal-regulated kinase 1/2 (ERK1/2) and p38 mitogen-activated protein kinase (MAPK). MAPK/ERK kinase 1/2 (MEK1/2) inhibitor, U0126, and p38 MAPK inhibitor, SB203580, blocked the CTRP3/cartducin-induced cell proliferation, and migration was blocked by U0126, but not the SB203580. Taken together, these results suggest that CTRP3/cartducin may be involved as a novel angiogenic factor in the formation of neointima following angioplasty.

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Year:  2007        PMID： 17534697     DOI： 10.1007/s11010-007-9506-6

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  21 in total

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Authors:  L A Liotta; E C Kohn
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3.  Temporal evolution of gene expression in rat carotid artery following balloon angioplasty.

Authors:  Jian-Ming Li; Xueqing Zhang; Peter R Nelson; Paul R Odgren; Janice D Nelson; Calin Vasiliu; Jane Park; Marvin Morris; Jane Lian; Bruce S Cutler; Peter E Newburger
Journal:  J Cell Biochem       Date:  2007-05-15       Impact factor: 4.429

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Authors:  K Pels; M Labinaz; C Hoffert; E R O'Brien
Journal:  Arterioscler Thromb Vasc Biol       Date:  1999-02       Impact factor: 8.311

Review 5.  Molecular mechanisms of blood vessel formation.

Authors:  F Bussolino; A Mantovani; G Persico
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6.  Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity.

Authors:  F Liu; A D Verin; P Wang; R Day; R P Wersto; F J Chrest; D K English; J G Garcia
Journal:  Am J Respir Cell Mol Biol       Date:  2001-06       Impact factor: 6.914

7.  Molecular cloning and characterization of a novel gene, CORS26, encoding a putative secretory protein and its possible involvement in skeletal development.

Authors:  T Maeda; M Abe; K Kurisu; A Jikko; S Furukawa
Journal:  J Biol Chem       Date:  2000-11-08       Impact factor: 5.157

8.  CTRP5 is a membrane-associated and secretory protein in the RPE and ciliary body and the S163R mutation of CTRP5 impairs its secretion.

Authors:  Md Nawajes A Mandal; Vidyullatha Vasireddy; G Bhanuprakash Reddy; Xiaofei Wang; Sayoko E Moroi; Bikash R Pattnaik; Bret A Hughes; John R Heckenlively; Peter F Hitchcock; Monica M Jablonski; Radha Ayyagari
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Review 9.  C1q and tumor necrosis factor superfamily: modularity and versatility.

Authors:  Uday Kishore; Christine Gaboriaud; Patrick Waters; Annette K Shrive; Trevor J Greenhough; Kenneth B M Reid; Robert B Sim; Gerard J Arlaud
Journal:  Trends Immunol       Date:  2004-10       Impact factor: 16.687

10.  Extracellular matrix changes in stented human coronary arteries.

Authors:  Andrew Farb; Frank D Kolodgie; Jin-Yong Hwang; Allen P Burke; Kirubel Tefera; Deena K Weber; Thomas N Wight; Renu Virmani
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  31 in total

1.  Regulation of the transcriptional activation of CTRP3 in chondrocytes by c-Jun.

Authors:  Mi-Jin Kim; Eun-Ju Park; Wan Lee; Jung-Eun Kim; Seung-Yoon Park
Journal:  Mol Cell Biochem       Date:  2012-05-30       Impact factor: 3.396

Review 2.  C1q/TNF-Related Protein 3 (CTRP3) Function and Regulation.

Authors:  Ying Li; Gary L Wright; Jonathan M Peterson
Journal:  Compr Physiol       Date:  2017-06-18       Impact factor: 9.090

Review 3.  The Role of Adipocytokines in Coronary Atherosclerosis.

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Journal:  Curr Atheroscler Rep       Date:  2017-02       Impact factor: 5.113

4.  Calcium and vitamin D3 combinations improve fatty liver disease through AMPK-independent mechanisms.

Authors:  Sara Shojaei Zarghani; Hamid Soraya; Mohammad Alizadeh
Journal:  Eur J Nutr       Date:  2016-12-17       Impact factor: 5.614

5.  Metabolic regulation by C1q/TNF-related protein-13 (CTRP13): activation OF AMP-activated protein kinase and suppression of fatty acid-induced JNK signaling.

Authors:  Zhikui Wei; Jonathan M Peterson; G William Wong
Journal:  J Biol Chem       Date:  2011-03-04       Impact factor: 5.157

6.  CTRP3 attenuates post-infarct cardiac fibrosis by targeting Smad3 activation and inhibiting myofibroblast differentiation.

Authors:  Dan Wu; Hong Lei; Jin-Yu Wang; Cheng-Lin Zhang; Han Feng; Feng-Ying Fu; Li Li; Li-Ling Wu
Journal:  J Mol Med (Berl)       Date:  2015-07-03       Impact factor: 4.599

7.  CTRP3 attenuates diet-induced hepatic steatosis by regulating triglyceride metabolism.

Authors:  Jonathan M Peterson; Marcus M Seldin; Zhikui Wei; Susan Aja; G William Wong
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2013-06-06       Impact factor: 4.052

Review 8.  Structural commonality of C1q TNF-related proteins and their potential to activate relaxin/insulin-like family peptide receptor 1 signalling pathways in cancer cells.

Authors:  Thomas Klonisch; Aleksandra Glogowska; Thatchawan Thanasupawat; Maxwell Burg; Jerry Krcek; Marshall Pitz; Appalaraju Jaggupilli; Prashen Chelikani; G William Wong; Sabine Hombach-Klonisch
Journal:  Br J Pharmacol       Date:  2016-08-11       Impact factor: 8.739

Review 9.  Metabolic function of the CTRP family of hormones.

Authors:  Marcus M Seldin; Stefanie Y Tan; G William Wong
Journal:  Rev Endocr Metab Disord       Date:  2014-06       Impact factor: 6.514

10.  CTRP3 deficiency reduces liver size and alters IL-6 and TGFβ levels in obese mice.

Authors:  Risa M Wolf; Xia Lei; Zhi-Chun Yang; Maeva Nyandjo; Stefanie Y Tan; G William Wong
Journal:  Am J Physiol Endocrinol Metab       Date:  2015-12-15       Impact factor: 4.310
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