Literature DB >> 17534511

Nucleophilic aromatic substitution using Et3SiH/cat. t-Bu-P4 as a system for nucleophile activation.

Masahiro Ueno1, Misato Yonemoto, Masahiro Hashimoto, Andrew E H Wheatley, Hiroshi Naka, Yoshinori Kondo.   

Abstract

A novel type of deprotonative arylation of nucleophiles was conducted using Et(3)SiH/cat. t-Bu-P4 and the powerful S(N)Ar reactions of aryl fluorides were accomplished using alcohols and malonates as nucleophiles.

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Year:  2007        PMID: 17534511     DOI: 10.1039/b700140a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Translation of microwave methodology to continuous flow for the efficient synthesis of diaryl ethers via a base-mediated S(N)Ar reaction.

Authors:  Charlotte Wiles; Paul Watts
Journal:  Beilstein J Org Chem       Date:  2011-10-04       Impact factor: 2.883

2.  Organocatalyzed Trifluoromethylation of Ketones and Sulfonyl Fluorides by Fluoroform under a Superbase System.

Authors:  Satoshi Okusu; Kazuki Hirano; Etsuko Tokunaga; Norio Shibata
Journal:  ChemistryOpen       Date:  2015-08-06       Impact factor: 2.911

  2 in total

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