Literature DB >> 17534244

Growth related oncogene-alpha (GRO-alpha): roles in atherosclerosis, angiogenesis and other inflammatory conditions.

Carlos Bechara1, Hong Chai, Peter H Lin, Qizhi Yao, Changyi Chen.   

Abstract

Growth related oncogene-alpha (GRO-alpha) is a member of the CXC chemokine family with an internal glutamate-leucine-arginine (ELR) motif. It was initially isolated and characterized by its growth stimulatory activity on malignant melanoma cells. Recently, many new functions and properties of GRO-alpha have been discovered and associated with atherosclerosis, angiogenesis and many inflammatory conditions. Purpose of this review is to overview current advances of multiple functions of GRO-alpha and its associated molecular mechanisms and clinical implications. We hope to further evaluate this molecule in the pathogenesis of atherosclerosis as well as angiogenesis to promote a background for therapeutic interventions.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17534244

Source DB:  PubMed          Journal:  Med Sci Monit        ISSN： 1234-1010


  28 in total

1.  Interleukin-33 induces growth-regulated oncogene-α expression and secretion in human umbilical vein endothelial cells.

Authors:  Masayoshi Yamamoto; Katsuyuki Umebashi; Akinori Tokito; Junichi Imamura; Michihisa Jougasaki
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2017-06-21       Impact factor: 3.619

2.  Neuregulin-1β induces proliferation, survival and paracrine signaling in normal human cardiac ventricular fibroblasts.

Authors:  Annet Kirabo; Sergey Ryzhov; Manisha Gupte; Seng Sengsayadeth; Richard J Gumina; Douglas B Sawyer; Cristi L Galindo
Journal:  J Mol Cell Cardiol       Date:  2017-03-03       Impact factor: 5.000

3.  Sulforaphane inhibits mammary adipogenesis by targeting adipose mesenchymal stem cells.

Authors:  Qinglin Li; Jixiang Xia; Yuan Yao; Da-Wei Gong; Hongfei Shi; Qun Zhou
Journal:  Breast Cancer Res Treat       Date:  2013-09-04       Impact factor: 4.872

4.  Combined treatment with bexarotene and rosuvastatin reduces angiotensin-II-induced abdominal aortic aneurysm in apoE(-/-) mice and angiogenesis.

Authors:  P Escudero; A Navarro; C Ferrando; E Furio; H Gonzalez-Navarro; M Juez; M J Sanz; L Piqueras
Journal:  Br J Pharmacol       Date:  2015-03-26       Impact factor: 8.739

5.  Oral microbial biofilm stimulation of epithelial cell responses.

Authors:  Rebecca Peyyala; Sreenatha S Kirakodu; Karen F Novak; Jeffrey L Ebersole
Journal:  Cytokine       Date:  2012-01-21       Impact factor: 3.861

6.  Early gestation chorionic villi-derived stromal cells for fetal tissue engineering.

Authors:  Lee Lankford; Taryn Selby; James Becker; Volodymyr Ryzhuk; Connor Long; Diana Farmer; Aijun Wang
Journal:  World J Stem Cells       Date:  2015-01-26       Impact factor: 5.326

7.  A potential role of the GRO-α/CXCR2 system in Sjögren's syndrome: regulatory effects of pro-inflammatory cytokines.

Authors:  Sabrina Lisi; Margherita Sisto; Dario Domenico Lofrumento; Massimo D'Amore; Raffaella De Lucro; Domenico Ribatti
Journal:  Histochem Cell Biol       Date:  2012-10-05       Impact factor: 4.304

8.  Macrophage-derived tumor necrosis factor-alpha is an early component of the molecular cascade leading to angiogenesis in response to aortic injury.

Authors:  Giovanni Ligresti; Alfred C Aplin; Penelope Zorzi; Ann Morishita; Roberto F Nicosia
Journal:  Arterioscler Thromb Vasc Biol       Date:  2011-03-03       Impact factor: 8.311

9.  Hypertension and Circulating Cytokines and Angiogenic Factors in Patients With Advanced Non-Clear Cell Renal Cell Carcinoma Treated With Sunitinib: Results From a Phase II Trial.

Authors:  Mehmet Asim Bilen; Amado J Zurita; Nasreen A Ilias-Khan; Hsiang-Chun Chen; Xuemei Wang; Alper Y Kearney; Sherie Hodges; Eric Jonasch; Shixia Huang; Aarif Yusuf Khakoo; Nizar M Tannir
Journal:  Oncologist       Date:  2015-08-25

10.  Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium.

Authors:  Yehoshua Maor; Jinlong Yu; Paula M Kuzontkoski; Bruce J Dezube; Xuefeng Zhang; Jerome E Groopman
Journal:  Genes Cancer       Date:  2012-07
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.