Literature DB >> 17531966

A web server for automatic analysis and extraction of relevant biological knowledge.

Juan Cedano1, Mario Huerta, Irene Estrada, Frederic Ballllosera, Oscar Conchillo, Pedro Delicado, Enrique Querol.   

Abstract

MOTIVATION: This application aims at assisting researchers with the extraction of significant medical and biological knowledge from data sets with complex relationships among their variables.
RESULTS: Non-hypothesis-driven approaches like Principal Curves of Oriented Points (PCOP) are a very suitable method for this objective. PCOP allows for obtaining of a representative pattern from a huge quantity of data of independent variables in a very flexible and direct way. A web server has been designed to automatically realize 'non-linear pattern' analysis, 'hidden-variable-dependent' clustering, and new samples 'local-dispersion-dependent' classification from the data involving new statistical techniques using the PCOP calculus. The tools facilitate the managing, comparison and visualization of results in a user-friendly graphical interface. AVAILABILITY: http://ibb.uab.es/revresearch.

Mesh:

Year:  2007        PMID: 17531966     DOI: 10.1016/j.compbiomed.2007.03.008

Source DB:  PubMed          Journal:  Comput Biol Med        ISSN: 0010-4825            Impact factor:   4.589


  2 in total

1.  NCR-PCOPGene: An Exploratory Tool for Analysis of Sample-Classes Effect on Gene-Expression Relationships.

Authors:  Juan Cedano; Mario Huerta; Enrique Querol
Journal:  Adv Bioinformatics       Date:  2008-12-10

2.  PCOPGene-Net: holistic characterisation of cellular states from microarray data based on continuous and non-continuous analysis of gene-expression relationships.

Authors:  Mario Huerta; Juan Cedano; Dario Peña; Antonio Rodriguez; Enrique Querol
Journal:  BMC Bioinformatics       Date:  2009-05-09       Impact factor: 3.169

  2 in total

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