Literature DB >> 17530210

[Congenital hemiplegia. A disease with manifold problems].

C Panteliadis1, M Tzitiridou, E Pavlidou, C Hagel, A Covanis, G Jacobi.   

Abstract

Congenital hemiplegia, defined as unilateral motor disability, is the hemiplegic type of cerebral palsy. The prevalence of congenital hemiplegia is estimated to be about 0.41-0.79/1000 live births. We examined 223 children (122 boys and 101 girls) suffering from congenital hemiplegia at the age of 3 months to 12 years. Mild hemiplegia was found in 31%, a moderate form in 48%, and a severe form in 21%. The upper limb was affected in more than half of the patients, only the lower extremity in one third, and both upper and lower limbs in 20%. Electroencephalographic abnormalities were found in 75.8% of the patients. The most frequent type of epilepsy was complex partial seizures (33%). Severity of the motor handicap, grade of EEG abnormalities, and the prevalence of epilepsy showed a significant correlation. The magnitude of the lesions in neuroimaging directly correlated with these three clinical variables, particularly in children with cortical and subcortical defects (84.2%). Strabismus was the most common visual impairment (17%), while hearing impairment was found in 8% of the patients. Of them, 38.3% showed no cognitive deficits, while those with severe congenital hemiplegia were found to have a lower intelligence quotient.

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Year:  2007        PMID: 17530210     DOI: 10.1007/s00115-007-2296-y

Source DB:  PubMed          Journal:  Nervenarzt        ISSN: 0028-2804            Impact factor:   1.214


  29 in total

Review 1.  A template for defining a causal relation between acute intrapartum events and cerebral palsy: international consensus statement.

Authors:  A MacLennan
Journal:  BMJ       Date:  1999-10-16

Review 2.  Cortical dysplasias and epilepsy: a review of the architectonic, clinical, and seizure patterns.

Authors:  F Andermann
Journal:  Adv Neurol       Date:  2000

Review 3.  Neurobiology of periventricular leukomalacia in the premature infant.

Authors:  J J Volpe
Journal:  Pediatr Res       Date:  2001-11       Impact factor: 3.756

4.  Memory for words and drawings in children with hemiplegic cerebral palsy.

Authors:  G Carlsson
Journal:  Scand J Psychol       Date:  1997-12

5.  [Congenital hemiplegia. Semiology, etiology and prognosis].

Authors:  F Goutieres; M J Challamel; J Aicardi; R Gilly
Journal:  Arch Fr Pediatr       Date:  1972-10

6.  Modified constraint-induced movement therapy for young children with hemiplegic cerebral palsy: a pilot study.

Authors:  C E Naylor; E Bower
Journal:  Dev Med Child Neurol       Date:  2005-06       Impact factor: 5.449

7.  The changing panorama of cerebral palsy in Sweden. VII. Prevalence and origin in the birth year period 1987-90.

Authors:  B Hagberg; G Hagberg; I Olow; L von Wendt
Journal:  Acta Paediatr       Date:  1996-08       Impact factor: 2.299

Review 8.  Mechanisms underlying epileptogenesis in cortical malformations.

Authors:  K M Jacobs; V N Kharazia; D A Prince
Journal:  Epilepsy Res       Date:  1999-09       Impact factor: 3.045

9.  Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the Commission on Classification and Terminology of the International League Against Epilepsy.

Authors: 
Journal:  Epilepsia       Date:  1981-08       Impact factor: 5.864

Review 10.  Stroke in newborn infants.

Authors:  Karin B Nelson; John K Lynch
Journal:  Lancet Neurol       Date:  2004-03       Impact factor: 44.182

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