PURPOSE: To evaluate the central corneal thickness (CCT) of Africans in a glaucoma practice in a university teaching hospital in West Nigeria, Africa, and compare results with similar studies carried out in African American and Afro-Caribbean populations. METHODS: CCT was measured by means of ultrasound pachymetry (pachymeter used was Micropach 200 P+ Pachymeter; Sonomed) in only African participants with either glaucomatous or healthy eyes. After instillation of topical anesthetic, 3 measurements of corneal thickness were taken, and the average thickness for each was calculated. The relationship between CCT and age was studied using correlation analyses and t tests. A total of 70 eyes were included for analysis. RESULTS: The mean CCT of all participants was 532.00 microm. Glaucoma suspects and patients with glaucoma had corneas thinner than those of normal participants (527.36 and 536.91 microm, respectively); however, the difference was not significant (P = 0.296). Decreasing values of CCT were significantly related to older age (P = 0.002). Men had a significantly higher CCT than women (P = 0.035). CONCLUSIONS: CCT values in African populations are less than those of whites. Decreasing values of CCT are significantly related to older age, and men have thicker corneas than women. There is a suggestion that CCT is lower in patients with glaucoma than in nonglaucomatous controls; however, the difference is not statistically significant. Comparing our results to other studies in literature, it seems that average CCT is similar between populations living in sub-Saharan Africa and African Americans and Afro-Caribbeans.
PURPOSE: To evaluate the central corneal thickness (CCT) of Africans in a glaucoma practice in a university teaching hospital in West Nigeria, Africa, and compare results with similar studies carried out in African American and Afro-Caribbean populations. METHODS: CCT was measured by means of ultrasound pachymetry (pachymeter used was Micropach 200 P+ Pachymeter; Sonomed) in only African participants with either glaucomatous or healthy eyes. After instillation of topical anesthetic, 3 measurements of corneal thickness were taken, and the average thickness for each was calculated. The relationship between CCT and age was studied using correlation analyses and t tests. A total of 70 eyes were included for analysis. RESULTS: The mean CCT of all participants was 532.00 microm. Glaucoma suspects and patients with glaucoma had corneas thinner than those of normal participants (527.36 and 536.91 microm, respectively); however, the difference was not significant (P = 0.296). Decreasing values of CCT were significantly related to older age (P = 0.002). Men had a significantly higher CCT than women (P = 0.035). CONCLUSIONS: CCT values in African populations are less than those of whites. Decreasing values of CCT are significantly related to older age, and men have thicker corneas than women. There is a suggestion that CCT is lower in patients with glaucoma than in nonglaucomatous controls; however, the difference is not statistically significant. Comparing our results to other studies in literature, it seems that average CCT is similar between populations living in sub-Saharan Africa and African Americans and Afro-Caribbeans.
Authors: T Desronvil; D Logan-Wyatt; W Abdrabou; M Triana; R Jones; S Taheri; E Del Bono; L R Pasquale; M Olivier; J L Haines; B J Fan; J L Wiggs Journal: Mol Vis Date: 2010-10-29 Impact factor: 2.367
Authors: Ta C Chang; Linda Celestin; Elizabeth A Hodapp; Alana L Grajewski; Anna Junk; Adam L Rothman; Eric R H Duerr; Swarup S Swaminathan; Steven J Gedde; Terri L Young; Janey Wiggs; Mildred M G Olivier; Raquel Quintanilla; Esdras Arrieta; Eleonore J Savatovsky; Elizabeth A Vanner; Richard K Parrish Journal: J Glaucoma Date: 2022-02-08 Impact factor: 2.290
Authors: Nauman Hashmani; Sharif Hashmani; Azfar N Hanfi; Misbah Ayub; Choudhry M Saad; Hina Rajani; Marium G Muhammad; Misbahul Aziz Journal: Clin Ophthalmol Date: 2017-06-30