Literature DB >> 17524883

Does renal transplantation improve erectile dysfunction in hemodialysed patients? What is the role of associated factors?

G Pourmand1, A Emamzadeh, S Moosavi, A Mehrsai, M Taherimahmoudi, M Nikoobakht, A Saraji, S Salem.   

Abstract

OBJECTIVE: To assess the effect of successful renal transplantation on improvement of erectile function in hemodialysis (HD) patients and the relationship between the degree of patient response and other factors.
MATERIALS AND METHODS: From September 2002 to November 2005, erectile function of 64 patients on HD for at least 6 months was evaluated pretransplantation and 6 months posttransplantation by International Index of Erectile Function, version 5 (IIEF-5). Sixty four age-matched persons without renal impairment were enrolled as control group to compare erectile dysfunction (ED) prevalence with the HD group. We evaluated duration of HD, age, and site of arterial anastomosis. In an attempt to find predictors of improvement of ED, after kidney transplantation, we performed linear regression analysis with a backward method.
RESULTS: The prevalence of ED in HD patients was 87.5%. Although there were some differences in the prevalence of ED between patients older versus younger than 50 years, the difference was not statistically significant. There was no relationship between the duration of dialysis and the severity of ED in HD group. Compared to the pretransplant IIEF-5 score (13.59), there was significant improvement (19.16). In an attempt to find predictors of ED improvement, we used a linear regression analysis with backward method. Pretransplant IIEF-5 score, age at the time of transplant, and anastomosis to the common iliac artery showed significant associations with improvement, but the duration of dialysis and anastomosis to internal iliac or external iliac artery did not.
CONCLUSION: The incidence of ED among hemodialyzed patients is high. Kidney transplantation is the key treatment for this complaint. ED has a major negative impact on the quality of life and family relations. Its treatment is associated with improvement of psychogenic factors. ED is a sensitive topic and many patients will not spontaneously discuss it with their physician, so better to include potency evaluation in posttransplantation list evaluations.

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Year:  2007        PMID: 17524883     DOI: 10.1016/j.transproceed.2007.03.038

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  6 in total

1.  Erectile function after kidney transplantation: a meta-analysis.

Authors:  Jiaqi Kang; Jia Tian; Yi Lu; Yuxuan Song; Xiaoqiang Liu
Journal:  Transl Androl Urol       Date:  2020-10

2.  [Sexuality after kidney transplantation].

Authors:  T Steiner; H Wunderlich; U Ott
Journal:  Urologe A       Date:  2009-12       Impact factor: 0.639

3.  Sildenafil citrate can improve erectile dysfunction among chronic hemodialysis patients.

Authors:  A Ghafari; B Farshid; A T Afshari; N Sepehrvand; E Rikhtegar; K Ghasemi; S Hatami
Journal:  Indian J Nephrol       Date:  2010-07

4.  Effects of renal transplantation on erectile dysfunction: a systematic review and meta-analysis.

Authors:  Irham Arif Rahman; Nur Rasyid; Ponco Birowo; Widi Atmoko
Journal:  Int J Impot Res       Date:  2021-06-08       Impact factor: 2.408

Review 5.  Male Sexual Dysfunction and Chronic Kidney Disease.

Authors:  Matthew M Edey
Journal:  Front Med (Lausanne)       Date:  2017-03-22

6.  The Impact of Hemodialysis on Sexual Function in Male Patients using the International Index of Erectile Function Questionnaire (IIEF).

Authors:  Hossein Savadi; Morteza Khaki; Maryam Javnbakht; Hasan Pourrafiee
Journal:  Electron Physician       Date:  2016-05-25
  6 in total

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