Literature DB >> 17523650

Fumimycin: a peptide deformylase inhibitor with an unusual skeleton produced by Aspergillus fumisynnematus.

Yun-Ju Kwon1, Mi-Jin Sohn, Chang-Ji Zheng, Won-Gon Kim.   

Abstract

Fumimycin, an unusual metabolite incorporating an unusual alanine unit linked to a phenyl group at the alpha-carbon with both lactone and amide moieties, was isolated from cultures of Aspergillus fumisynnematus. Its structure was established by spectral analysis. Fumimycin was found to inhibit Staphylococcus aureus peptide deformylase with an IC50 value of 4.1 microM and also showed antibacterial activity against S. aureus.

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Year:  2007        PMID： 17523650     DOI： 10.1021/ol0703231

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  11 in total

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Journal:  Beilstein J Org Chem       Date:  2011-11-25       Impact factor: 2.883

Review 4.  Extrolites of Aspergillus fumigatus and Other Pathogenic Species in Aspergillus Section Fumigati.

Authors:  Jens C Frisvad; Thomas O Larsen
Journal:  Front Microbiol       Date:  2016-01-07       Impact factor: 5.640

5.  Synthesis of Benzofuran-2-One Derivatives and Evaluation of Their Antioxidant Capacity by Comparing DPPH Assay and Cyclic Voltammetry.

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Review 6.  Secondary metabolites (SMs) of Isaria cicadae and Isaria tenuipes.

Authors:  Xiaofeng Zhang; Qiongbo Hu; Qunfang Weng
Journal:  RSC Adv       Date:  2018-12-21       Impact factor: 4.036

7.  Polyphasic taxonomy of Aspergillus section Fumigati and its teleomorph Neosartorya.

Authors:  R A Samson; S Hong; S W Peterson; J C Frisvad; J Varga
Journal:  Stud Mycol       Date:  2007       Impact factor: 16.097

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Journal:  BMC Genomics       Date:  2017-08-30       Impact factor: 3.969

9.  Chiral phosphine-catalyzed tunable cycloaddition reactions of allenoates with benzofuranone-derived olefins for a highly regio-, diastereo- and enantioselective synthesis of spiro-benzofuranones.

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Journal:  Chem Sci       Date:  2015-09-15       Impact factor: 9.825

10.  Organs, Cultivars, Soil, and Fruit Properties Affect Structure of Endophytic Mycobiota of Pinggu Peach Trees.

Authors:  Fei Ren; Wei Dong; Dong-Hui Yan
Journal:  Microorganisms       Date:  2019-09-05
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