| Literature DB >> 17523017 |
M Zhou1, A Zhang, B Lin, J Liu, L X Xu.
Abstract
Genetic response of human umbilical vein cells (HUVECs) to heat shock was studied using gene expression analysis. HUVECs were subjected to heat treatment at 44 degrees C and 55 degrees C for 1 h, respectively. Four hours after the treatment, gene expression of the treated cells and control cells (37 degrees C) were profiled using cDNA microarray. Data were analyzed using bioinformatics tools, and the results were verified by real-time quantitative PCR experiment. It has been shown that a large number of genes were regulated indicating global response to heat treatment at the genetic level.Entities:
Mesh：
Year: 2007 PMID： 17523017 DOI： 10.1080/02656730701295441
Source DB: PubMed Journal: Int J Hyperthermia ISSN： 0265-6736 Impact factor: 3.914