Literature DB >> 17521194

Abyssomicin E, a highly functionalized polycyclic metabolite from Streptomyces species.

Xue-Mei Niu1, Sheng-Hong Li, Helmar Görls, Dieter Schollmeyer, Matthias Hilliger, Susanne Grabley, Isabel Sattler.   

Abstract

Abyssomicin E (1), a new polycyclic metabolite with a C19 skeleton, was isolated from Streptomyces sp. (HKI0381). Its chemical structure was determined by comprehensive NMR and MS spectroscopic analyses. For the first time in this recently discovered class of compounds, the absolute stereochemistry was directly established by subsequent single-crystal X-ray diffraction study using anomalous dispersion with copper radiation.

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Year:  2007        PMID： 17521194     DOI： 10.1021/ol0705999

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  11 in total

1.  Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-6-2.

Authors:  Xiachang Wang; Sherif I Elshahawi; Wenlong Cai; Yinan Zhang; Larissa V Ponomareva; Xiabin Chen; Gregory C Copley; James C Hower; Chang-Guo Zhan; Sean Parkin; Jürgen Rohr; Steven G Van Lanen; Khaled A Shaaban; Jon S Thorson
Journal:  J Nat Prod       Date:  2017-03-30       Impact factor: 4.050

Review 2.  Novel anti-infective compounds from marine bacteria.

Authors:  Hafizur Rahman; Brian Austin; Wilfrid J Mitchell; Peter C Morris; Derek J Jamieson; David R Adams; Andrew Mearns Spragg; Michael Schweizer
Journal:  Mar Drugs       Date:  2010-03-05       Impact factor: 5.118

3.  Design and Synthesis of Molecular Scaffolds with Anti-infective Activity.

Authors:  Junjia Liu; T Aaron Bedell; Julian G West; Erik J Sorensen
Journal:  Tetrahedron       Date:  2016-01-28       Impact factor: 2.457

Review 4.  Spirotetronate polyketides as leads in drug discovery.

Authors:  Michelle H Lacoske; Emmanuel A Theodorakis
Journal:  J Nat Prod       Date:  2014-12-01       Impact factor: 4.050

5.  Characterization and heterologous expression of the neoabyssomicin/abyssomicin biosynthetic gene cluster from Streptomyces koyangensis SCSIO 5802.

Authors:  Jiajia Tu; Siting Li; Jiang Chen; Yongxiang Song; Shaobin Fu; Jianhua Ju; Qinglian Li
Journal:  Microb Cell Fact       Date:  2018-02-20       Impact factor: 5.328

Review 6.  Concepts and Methods to Access Novel Antibiotics from Actinomycetes.

Authors:  Joachim J Hug; Chantal D Bader; Maja Remškar; Katarina Cirnski; Rolf Müller
Journal:  Antibiotics (Basel)       Date:  2018-05-22

Review 7.  Review on Abyssomicins: Inhibitors of the Chorismate Pathway and Folate Biosynthesis.

Authors:  Carmen Sadaka; Edmund Ellsworth; Paul Robert Hansen; Richard Ewin; Peter Damborg; Jeffrey L Watts
Journal:  Molecules       Date:  2018-06-06       Impact factor: 4.411

Review 8.  Abyssomicins-A 20-Year Retrospective View.

Authors:  Hans-Peter Fiedler
Journal:  Mar Drugs       Date:  2021-05-24       Impact factor: 5.118

9.  Abyssomicins from the South China Sea deep-sea sediment Verrucosispora sp.: natural thioether Michael addition adducts as antitubercular prodrugs.

Authors:  Qian Wang; Fuhang Song; Xue Xiao; Pei Huang; Li Li; Aaron Monte; Wael M Abdel-Mageed; Jian Wang; Hui Guo; Wenni He; Feng Xie; Huanqin Dai; Miaomiao Liu; Caixia Chen; Hao Xu; Mei Liu; Andrew M Piggott; Xueting Liu; Robert J Capon; Lixin Zhang
Journal:  Angew Chem Int Ed Engl       Date:  2012-12-06       Impact factor: 15.336

10.  The crystal structure of AbsH3: A putative flavin adenine dinucleotide-dependent reductase in the abyssomicin biosynthesis pathway.

Authors:  Jonathan A Clinger; Xiachang Wang; Wenlong Cai; Yanyan Zhu; Mitchell D Miller; Chang-Guo Zhan; Steven G Van Lanen; Jon S Thorson; George N Phillips
Journal:  Proteins       Date:  2020-10-21
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