Literature DB >> 17520523

Novel epoxyfuranoid lignans and antitubercular constituents from the leaves of Beilschmiedia tsangii.

Jih-Jung Chen1, En-Tzu Chou, Chien-Fang Peng, Ih-Sheng Chen, Sheng-Zehn Yang, Hung-Yi Huang.   

Abstract

Three new epoxyfuranoid lignans, 4alpha,5alpha-epoxybeilschmin A (1), 4alpha,5alpha-epoxybeilschmin B (2), and beilschmin D (3), together with nine known compounds have been isolated from the leaves of Beilschmiedia tsangii. The structures of these new compounds were determined through spectral analyses. Among the isolates, beilschmin A (4) and beilschmin B (5) exhibited potent antitubercular activities (MICs = 2.5 and 7.5 microg/mL, respectively) against Mycobacterium tuberculosis 90 - 221387 in vitro.

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Year:  2007        PMID： 17520523     DOI： 10.1055/s-2007-967195

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  10 in total

Review 1.  Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae).

Authors:  Bruno Ndjakou Lenta; Jean Rodolphe Chouna; Pepin Alango Nkeng-Efouet; Norbert Sewald
Journal:  Biomolecules       Date:  2015

2.  Antibacterial activities of Beilschmiedia obscura and six other Cameroonian medicinal plants against multi-drug resistant Gram-negative phenotypes.

Authors:  Aimé G Fankam; Jules R Kuiate; Victor Kuete
Journal:  BMC Complement Altern Med       Date:  2014-07-14       Impact factor: 3.659

Review 3.  Plants in our combating strategies against Mycobacterium tuberculosis: progress made and obstacles met.

Authors:  Vivek Kumar Gupta; M Madhan Kumar; Deepa Bisht; Anupam Kaushik
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

4.  (6,7-Dimethoxy-4-methylisoquinolinyl)-(4'-methoxyphenyl)-methanone, a new benzylisoquinoline alkaloid from Beilschmiedia brevipes.

Authors:  Pratiwi Pudjiastuti; Mat Ropi Mukhtar; A Hamid A Hadi; Nurdin Saidi; Hiroshi Morita; Marc Litaudon; Khalijah Awang
Journal:  Molecules       Date:  2010-03-31       Impact factor: 4.411

5.  (+)-Kunstlerone, a new antioxidant neolignan from the Leaves of Beilschmiedia kunstleri gamble.

Authors:  Abbas Mollataghi; A Hamid A Hadi; Khalijah Awang; Jamaludin Mohamad; Marc Litaudon; Mat Ropi Mukhtar
Journal:  Molecules       Date:  2011-08-04       Impact factor: 4.411

Review 6.  The potential of plant systems to break the HIV-TB link.

Authors:  Peyman Habibi; Henry Daniell; Carlos Ricardo Soccol; Maria Fatima Grossi-de-Sa
Journal:  Plant Biotechnol J       Date:  2019-07-18       Impact factor: 9.803

7.  Molecular Docking Suggests the Targets of Anti-Mycobacterial Natural Products.

Authors:  Rafael Baptista; Sumana Bhowmick; Jianying Shen; Luis A J Mur
Journal:  Molecules       Date:  2021-01-18       Impact factor: 4.411

8.  Secondary metabolites from the roots of Beilschmiedia tsangii and their anti-inflammatory activities.

Authors:  Yun-Ting Huang; Hsun-Shuo Chang; Guei-Jane Wang; Chu-Hung Lin; Ih-Sheng Chen
Journal:  Int J Mol Sci       Date:  2012-12-03       Impact factor: 5.923

9.  In vitro antibacterial and antibiotic-potentiation activities of the methanol extracts from Beilschmiedia acuta, Clausena anisata, Newbouldia laevis and Polyscias fulva against multidrug-resistant Gram-negative bacteria.

Authors:  Simplice B Tankeo; Pierre Tane; Victor Kuete
Journal:  BMC Complement Altern Med       Date:  2015-11-22       Impact factor: 3.659

Review 10.  Chemical constituents and bioactivity of Formosan lauraceous plants.

Authors:  Hsun-Shuo Chang; Ih-Sheng Chen
Journal:  J Food Drug Anal       Date:  2016-01-05       Impact factor: 6.157
  10 in total

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