Literature DB >> 17520140

"O-acyl isopeptide method" for peptide synthesis: synthesis of forty kinds of "O-acyl isodipeptide unit" Boc-Ser/Thr(Fmoc-Xaa)-OH.

Taku Yoshiya1, Atsuhiko Taniguchi, Youhei Sohma, Fukue Fukao, Setsuko Nakamura, Naoko Abe, Nui Ito, Mariusz Skwarczynski, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso.   

Abstract

The O-acyl isopeptide method has recently received attention as an efficient synthetic method for peptides. Herein, forty kinds of "O-acyl isodipeptide unit" Boc-Ser/Thr(Fmoc-Xaa)-OH (1-40) were effectively synthesized in two-steps without epimerization. The O-acyl isodipeptide units are important building blocks to enable the routine use of the O-acyl isopeptide method.

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Year:  2007        PMID： 17520140     DOI： 10.1039/b702284k

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  2 in total

1.  Synthesis and Characterization of an A6-A11 Methylene Thioacetal Human Insulin Analogue with Enhanced Stability.

Authors:  Nan Zheng; Prasoona Karra; Michael A VandenBerg; Jin Hwan Kim; Matthew J Webber; William L Holland; Danny Hung-Chieh Chou
Journal:  J Med Chem       Date:  2019-12-13       Impact factor: 7.446

Review 2.  A Global Review on Short Peptides: Frontiers and Perspectives.

Authors:  Vasso Apostolopoulos; Joanna Bojarska; Tsun-Thai Chai; Sherif Elnagdy; Krzysztof Kaczmarek; John Matsoukas; Roger New; Keykavous Parang; Octavio Paredes Lopez; Hamideh Parhiz; Conrad O Perera; Monica Pickholz; Milan Remko; Michele Saviano; Mariusz Skwarczynski; Yefeng Tang; Wojciech M Wolf; Taku Yoshiya; Janusz Zabrocki; Piotr Zielenkiewicz; Maha AlKhazindar; Vanessa Barriga; Konstantinos Kelaidonis; Elham Mousavinezhad Sarasia; Istvan Toth
Journal:  Molecules       Date:  2021-01-15       Impact factor: 4.411
  2 in total

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