Literature DB >> 17520

Isolation and identification of the major metabolite of albuterol in human urine.

C Lin, Y Li, J McGlotten, J B Morton, S Symchowicz.   

Abstract

The major urinary metabolite of albuterol in man was isolated and purified by ion-exchange chromatography and countercurrent distribution. On the basis of proton magnetic resonance, infrared, and mass-spectral analysis, enzymic hydrolysis, and assay of inorganic sulfate after acid hydrolysis, the metabolite has been identified as the 4'-O-sulfate ester of albuterol.

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Year:  1977        PMID: 17520

Source DB:  PubMed          Journal:  Drug Metab Dispos        ISSN: 0090-9556            Impact factor:   3.922


  9 in total

1.  Sulfation of ractopamine and salbutamol by the human cytosolic sulfotransferases.

Authors:  Kyounga Ko; Katsuhisa Kurogi; Garrett Davidson; Ming-Yih Liu; Yoichi Sakakibara; Masahito Suiko; Ming-Cheh Liu
Journal:  J Biochem       Date:  2012-07-04       Impact factor: 3.387

2.  Stereoselective metabolism of RS-albuterol in humans.

Authors:  T Walle; E A Eaton; U K Walle; G R Pesola
Journal:  Clin Rev Allergy Immunol       Date:  1996       Impact factor: 8.667

Review 3.  The pharmacokinetics of levosalbutamol: what are the clinical implications?

Authors:  D W Boulton; J P Fawcett
Journal:  Clin Pharmacokinet       Date:  2001-01       Impact factor: 6.447

4.  Pharmacokinetics and metabolism of salbutamol in premature labour.

Authors:  M J Hutchings; J D Paull; E Wilson-Evered; D J Morgan
Journal:  Br J Clin Pharmacol       Date:  1987-07       Impact factor: 4.335

5.  The pharmacokinetics of metoclopramide in man with observations in the dog.

Authors:  D N Bateman; C Kahn; D S Davies
Journal:  Br J Clin Pharmacol       Date:  1980-04       Impact factor: 4.335

Review 6.  Enantioselective disposition of albuterol in humans.

Authors:  D W Boulton; J P Fawcett
Journal:  Clin Rev Allergy Immunol       Date:  1996       Impact factor: 8.667

7.  Stereoselective sulphate conjugation of salbutamol in humans: comparison of hepatic, intestinal and platelet activity.

Authors:  U K Walle; G R Pesola; T Walle
Journal:  Br J Clin Pharmacol       Date:  1993-04       Impact factor: 4.335

8.  Salbutamol disposition and dynamics in conscious rabbits: influence of the route of administration and of the dose.

Authors:  S Perreault; H Ong; P du Souich
Journal:  J Pharmacokinet Biopharm       Date:  1992-10

Review 9.  Clinical pharmacokinetics of beta-agonists.

Authors:  D J Morgan
Journal:  Clin Pharmacokinet       Date:  1990-04       Impact factor: 6.447

  9 in total

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