Literature DB >> 17516391

Cidofovir and foscarnet for treatment of human herpesvirus 6 encephalitis in a neutropenic stem cell transplant recipient.

Christoph Pöhlmann1, Johannes Schetelig, Ulrike Reuner, Martin Bornhäuser, Thomas Illmer, Alexander Kiani, Gerhard Ehninger, Enno Jacobs, Jacques Rohayem.   

Abstract

We report a stem cell transplant recipient who developed human herpesvirus 6 encephalitis. Human herpesvirus 6 load indicated massive intrathecal viral replication. Administration of cidofovir followed by foscarnet was associated with total clearance of human herpesvirus 6 infection. Cidofovir and foscarnet combination therapy may be beneficial for reducing mortality of (neutropenic) stem cell transplant recipients with human herpesvirus 6 encephalitis.

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Year:  2007        PMID： 17516391     DOI： 10.1086/518282

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  14 in total

1.  High human herpesvirus 6 viral load in pediatric allogeneic hematopoietic stem cell transplant patients is associated with detection in end organs and high mortality.

Authors:  Lena E Winestone; Rajesh Punn; John S Tamaresis; Julia Buckingham; Benjamin A Pinsky; Jesse J Waggoner; Sandhya Kharbanda
Journal:  Pediatr Transplant       Date:  2017-11-27

2.  A short tale of blood, kidney and brain: BK virus encephalitis in an allogeneic stem cell transplant recipient.

Authors:  C Bourlon; S Alamoudi; D Kumar; A Viswabandya; S Thyagu; F V Michelis; D D-H Kim; J H Lipton; H A Messner; U Deotare
Journal:  Bone Marrow Transplant       Date:  2017-02-20       Impact factor: 5.483

3.  Pathogen or Bystander: Clinical Significance of Detecting Human Herpesvirus 6 in Pediatric Cerebrospinal Fluid.

Authors:  Utsav Pandey; Alexander L Greninger; Greg R Levin; Keith R Jerome; Vikram C Anand; Jennifer Dien Bard
Journal:  J Clin Microbiol       Date:  2020-04-23       Impact factor: 5.948

Review 4.  Clinical practice recommendations for the diagnosis and management of human herpesvirus-6B encephalitis after allogeneic hematopoietic stem cell transplantation: the Japan Society for Hematopoietic Cell Transplantation.

Authors:  Masao Ogata; Naoyuki Uchida; Takahiro Fukuda; Kazuhiro Ikegame; Tomohiko Kamimura; Makoto Onizuka; Koji Kato; Hikaru Kobayashi; Yoji Sasahara; Masashi Sawa; Akihisa Sawada; Daiichiro Hasegawa; Masayoshi Masuko; Toshihiro Miyamoto; Shinichiro Okamoto
Journal:  Bone Marrow Transplant       Date:  2019-11-19       Impact factor: 5.483

5.  Fatal herpetic encephalitis during brain radiotherapy in a cerebral metastasized breast cancer patient.

Authors:  Tatiana Koudriavtseva; Emanuela Onesti; Riccardo Tonachella; Lorella Pelagalli; Antonello Vidiri; Bruno Jandolo
Journal:  J Neurooncol       Date:  2010-02-11       Impact factor: 4.130

Review 6.  The development of new therapies for human herpesvirus 6.

Authors:  Mark N Prichard; Richard J Whitley
Journal:  Curr Opin Virol       Date:  2014-10-22       Impact factor: 7.090

Review 7.  Human herpesvirus 6 infections after liver transplantation.

Authors:  Rima Camille Abdel Massih; Raymund R Razonable
Journal:  World J Gastroenterol       Date:  2009-06-07       Impact factor: 5.742

Review 8.  Acute viral infections of the central nervous system in immunocompetent adults: diagnosis and management.

Authors:  Marie Studahl; Lars Lindquist; Britt-Marie Eriksson; Göran Günther; Malin Bengner; Elisabeth Franzen-Röhl; Jan Fohlman; Tomas Bergström; Elisabeth Aurelius
Journal:  Drugs       Date:  2013-02       Impact factor: 9.546

9.  Guidelines for the Prevention and Treatment of Opportunistic Infections among HIV-exposed and HIV-infected children: recommendations from CDC, the National Institutes of Health, the HIV Medicine Association of the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics.

Authors:  Lynne M Mofenson; Michael T Brady; Susie P Danner; Kenneth L Dominguez; Rohan Hazra; Edward Handelsman; Peter Havens; Steve Nesheim; Jennifer S Read; Leslie Serchuck; Russell Van Dyke
Journal:  MMWR Recomm Rep       Date:  2009-09-04

Review 10.  Molecular diagnosis and management of viral infections in hematopoietic stem cell transplant recipients.

Authors:  Sabine Breuer; Margit Rauch; Susanne Matthes-Martin; Thomas Lion
Journal:  Mol Diagn Ther       Date:  2012-04-01       Impact factor: 4.476
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